Effect of caudal block on stress responses in children

Abstract

These results indicate that caudal anesthesia suppresses the metabolic and endocrine responses to stress associated with lower abdominal and genitourinary surgery in children.

Comparison of the effect of ketamine added to bupivacaine and ropivacaine, on stress hormone levels and the duration of caudal analgesia

“…a reduced insulin response at the cellular level (37). Reduced insulin levels have been shown during caudal anesthesia (38), but in our study insulin increased in group R ( P < 0.05). Further studies are required to explain this.…”

“…Thus normal regulation of glucose homeostasis is ineffective peri‐operatively, and hyperglycemia is ineluctable (37). Tuncer et al (38) measured glucose concentrations in patients who received caudal or general anesthesia. Glucose concentrations increased more in the controls than in the caudal group.…”

Comparison of the effects of clonidine and ketamine added to ropivacaine on stress hormone levels and the duration of caudal analgesia

“…We found only one study of insulin concentrations in children with caudal anesthesia: Tuncer et al assessed the effects of caudal block on plasma cortisol, prolactin, insulin and glucose concentrations during and after surgery. Mean insulin concentrations were lower in the caudal group than the control group (29). In our study insulin was increased only in group R ( P < 0.05).…”

Impact of Epidural Analgesia on Hemodynamics and Stress Markers in Children during Orthopedic Surgery

“…последнее десятилетие практика центральных блокад в педиатрической анестезиологии расширилась благода ря разработке качественных игл и катетеров для эпиду ральной анестезии и созданию принципиально нового ряда эффективных местных анестетиков [2][3][4]. Было показано, что регионарная анестезия, по сравнению с изолированным внутривенным обезболиванием, обес печивает более полноценную анальгезию [2,5,6], боль шую гемодинамическую стабильность [7][8][9], обладает более выраженным метаболическим стресс протектор ным эффектом [10,11].…”