Effect of Cardiopulmonary Bypass Duration on Thyroid Function Tests after Open Heart Surgery in Children

Saifeddine, Mahmoud; Rastghar, B.; Javid, Amir; Shiva, Shadi

doi:10.3923/jbs.2011.326.330

Cited by 2 publications

(2 citation statements)

References 2 publications

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“…Our study had similar results. The results in our study are similar to study conducted by Shiva et al (16) who found the effect of Short and long CPB procedure on Thyroid function Test. In the long CBP procedure TT4 before surgery, on 2 nd postoperative day and 7 th postoperative day was 8.04 ± 3.05 µg/dl, 6.61 ± 2.50 µg/dl and 8.03 ± 2.70 µg/dl.…”

Section: ⅳ Resultssupporting

confidence: 92%

Changes in Thyroid Function in Patients Undergoing Cardiac Surgery Using Cardiopulmonary Bypass

Juwhyreeyeh

Qayoom

Batul

2023

Gal Int J Health Sci Res

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INTRODUCTION: After open heart surgery (OHS) using cardiopulmonary bypass (CPB), abnormalities in the circulating thyroid hormone levels are found in the absence of primary thyroid disease; this is collectively called the sick euthyroid syndrome (SES). AIMS ANDOBJECTIVES: To study thyroid function test in patients planned for cardiac surgery under cardiopulmonary bypass. MATERIALS AND METHODS: This study included a total of 150 patients, of any age, either sex, planned for cardiac surgery under cardiopulmonary bypass (like Valve replacement, CABG, myxoma excision, congenital Heart Diseases like ASD, VSD, TOF). To assess the levels of thyroid hormone, TSH, TT3 and TT4 were measured. The blood samples were collected at regular intervals: preoperatively, on 2nd postoperative day and on 7th postoperative day. CONCLUSION: In our study the levels of thyroid hormone (TT4 and TT3) decreased significantly after cardiopulmonary bypass. Keywords: Open Heart Surgery (OHS), Cardiopulmonary Bypass (CPB), Sick Euthyroid Syndrome (SES)

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Section: ⅳ Resultssupporting

confidence: 92%

Changes in Thyroid Function in Patients Undergoing Cardiac Surgery Using Cardiopulmonary Bypass

Juwhyreeyeh

Qayoom

Batul

2023

Gal Int J Health Sci Res

View full text Add to dashboard Cite

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“…[5]. CPB simulates the effect of euthyroid sick syndrome [21], and the length of bypass time longer than 90 min increase the severity of hypothyroidism [22]. Pre-operative hypothyroidism may aggregate and amplify the low T3 syndrome, which negatively affects mortality rate and cardiac output after CABG [23].…”

Section: Discussionmentioning

confidence: 99%

Hypothyroidism Is Correlated with Ventilator Complications and Longer Hospital Days after Coronary Artery Bypass Grafting Surgery in a Relatively Young Population: A Nationwide, Population-Based Study

Lin

Kao

Tsai

et al. 2022

JCM

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Background: Some research indicated that hypothyroidism has huge adverse effects for the metabolic, cardiovascular, respiratory, and immune systems. However, there is no confirmed conclusion for the effect of cardiovascular surgery. This cohort study aims to investigate the prognosis of hypothyroidism patient at the age under 65-year-old after coronary artery bypass grafting (CABG) surgery. Method: From the National Health Insurance Research Database of Taiwan, 1586 patients with hypothyroidism who underwent elective CABG surgery were selected, along with 6334 patients who underwent surgery in a ratio of 1:4 sex-, age- and index year-matched controls, who were out of hypothyroidism. We used Cox proportional hazard analysis to compare the rate of 30-day, 5-year mortality, post-operative atrial fibrillation, respiratory complication during an average of 10-year follow-up. Result: Post-CABG patients had more hospital days, which was associated with hypothyroidism, male, DM and higher CCI_R (p < 0.001). Post-CABG patients had more inpatient respiratory complications, which was associated with hypothyroidism (p = 0.041), DM and CCI_R (p < 0.001, p = 0.046), and there was no difference in 1-year respiratory complication, tracheostomy in the same hospital course and within 1 year, repeated PCI, Af, CVVH, cerebral infarction, 30-day and 5-year mortality rate. Conclusions: Hypothyroidism correlates to post-CABG ventilator-related complications and pneumonia, and prolonged hospital days, but no effect on 30-day, 5-year mortality, post-operative atrial fibrillation and cerebral infarction rate. Thyroid function survey might include routinely preoperative survey for CABG outcome prognosis.

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Effect of Cardiopulmonary Bypass Duration on Thyroid Function Tests after Open Heart Surgery in Children

Cited by 2 publications

References 2 publications

Changes in Thyroid Function in Patients Undergoing Cardiac Surgery Using Cardiopulmonary Bypass

Changes in Thyroid Function in Patients Undergoing Cardiac Surgery Using Cardiopulmonary Bypass

Hypothyroidism Is Correlated with Ventilator Complications and Longer Hospital Days after Coronary Artery Bypass Grafting Surgery in a Relatively Young Population: A Nationwide, Population-Based Study

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