Effect of cancer history on post-resuscitation treatments in out-of-hospital cardiac arrest

Kang, Saee Byel; Kong, So Yeon; Shin, Sang Do; Ro, Young Sun; Song, Kyoung Jun; Hong, Ki Jeong; Kim, Tae Han

doi:10.1016/j.resuscitation.2019.02.005

Cited by 6 publications

(2 citation statements)

References 34 publications

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Section: Discussionmentioning

confidence: 99%

“…Previous studies have examined the survival to hospital discharge between patients with and without cancer 14 , 23 . Both of the two previous studies showed that patients with cancer had a lower survival rate than those without (31% vs. 46%), which is inconsistent with the results of our study, although Kang et al 23 investigated patients who underwent OHCA. Lower use of post-cardiac arrest management, such as angiography, PCI, TTM, and a smaller proportion of initial shockable rhythm in patients with cancer, was considered to be the major reason for the differences in survival rates; in support of this explanation, previous studies demonstrated that an initial shockable rhythm was associated with a higher rate of PCI due to its high likelihood of cardiac origin, which PCI could benefit 24 , 25 .…”

Section: Discussionmentioning

confidence: 99%

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The feasibility of extracorporeal cardiopulmonary resuscitation for patients with active cancer who undergo in-hospital cardiac arrest

Shin

Kang

Kim

et al. 2022

Sci Rep

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Indications of extracorporeal cardiopulmonary resuscitation (ECPR) are still debatable, particularly in patients with cancer. Prediction of the prognosis of in-hospital cardiac arrest (IHCA) in patients with cancer receiving ECPR is important given the increasing prevalence and survival rate of cancer. We compared the neurologic outcomes and survival rates of IHCA patients with and without cancer receiving ECPR. Data from the extracorporeal membrane oxygenation registry between 2015 and 2019 were used in a retrospective manner. The primary outcome was 6-month good neurologic outcome, defined as a Cerebral performance category score of 1 or 2. The secondary outcomes were 1- and 3-month good neurologic outcome, and 6-month survival. Among 247 IHCA patients with ECPR, 43 had active cancer. The 6-month good neurologic outcome rate was 27.9% and 32.4% in patients with and without active cancer, respectively (P > 0.05). Good neurologic outcomes at 1-month (30.2% vs. 20.6%) and 3-month (30.2% vs. 28.4%), and the survival rate at 6-month (39.5% vs. 36.5%) were not significantly different (all P > 0.05) Active cancer was not associated with 6-month good neurologic outcome by logistic regression analyses. Therefore, patients with IHCA should not be excluded from ECPR solely for the presence of cancer itself.

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Section: Discussionmentioning

confidence: 99%