Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes

Grbic, G.; Ćulić, Milka; Martać, Ljiljana; Soković, Marina; Spasić, Slađana; Dokovic, Dejan

doi:10.2298/abs0804547g

Cited by 10 publications

(7 citation statements)

References 16 publications

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“…On the other hand, the connection between the FD and H described by the formula FD = 2 -H [15] means that, during epileptic attacks, there is a decrease in the FD values. This was noticed in our recent study [13] where we mainly calculated the mean FD values of electrocortical activity without separation of the ictal vs interictal activity during121-sec-long sequences. This circumstance could mask the FD value during particularly short-lasting epileptiform discharges.…”

Section: Discussionmentioning

confidence: 96%

“…There are different approaches to the investigation of the neurophysiological mechanisms crucial for understanding of the processes of interictal-to-ictal transition in human epilepsy; these are, in particular, computational models of EEG activity [8] and experimental animal models [9,10]. We described some characteristic changes in the spectral, wavelet, and Higuchi's FD parameters of electrocortical activity in a rat model of acute seizures [9][10][11][12][13]. The aim of this study was to find characteristic changes in the H of parietal electrocortical activity by the comparative use of various methods in the rat acute model of epilepsy provoked by parenteral administrations of camphor essential oil or 1,8-cineole (the main constituent of this oil).…”

Section: Introductionmentioning

confidence: 99%

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Use of the Hurst Exponent for Analysis of Electrocortical Epileptiform Activity Induced in Rats by Administration of Camphor Essential Oil or 1,8-Cineole

et al. 2010

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In this study, we investigated the presence of long-range correlation effects in the electrocortical activity of rats using the Hurst exponent (H) calculated by dispersion analysis (DA) and an aggregated variance method (AGV). A slow decline of the autocorrelation function during time expansion and the existence of a correlation between distant time points of electrocorticograms (ECoGs) were shown to be typical of various pathophysiological states. In these cases, the H values were within a 0.5 < H < 1 range. A particularly slow decay of the autocorrelation function is typical of a long-range dependence (LRD). We found that ECoGs after i.p. administrations of camphor essential oil or its main constituent, 1,8-cineole, included attacks of uncontrolled electrical discharges and showed the presence of longrange correlation effects. Such findings are in agreement with recent data obtained by other authors and suggest that initiation of seizures can be predicted by certain ECoG indices. We estimated the critical period where the H values for ECoGs containing uncontrolled electrical discharges continuously increased within a few minutes before the attack. We believe that the AGV demonstrates certain advantages over DA in calculations of the H.

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Section: Discussionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

Use of the Hurst Exponent for Analysis of Electrocortical Epileptiform Activity Induced in Rats by Administration of Camphor Essential Oil or 1,8-Cineole

et al. 2010

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“…We are investigating applicability of traditional linear and nonlinear methods in some of the current problems such as brain injury [22][23][24][25], monitoring the depth of anaesthesia [26] and other applications in biomedicine [27]. In cases of less pronounced features the nonlinear analysis is providing additional insights.…”

Section: Conclusion and Discussionmentioning

confidence: 99%

Detection of Structural Features in Biological Signals

Stevanovic

Perović

Klonowski

et al. 2009

J Sign Process Syst Sign Image Video Technol

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In this article structures in biological signals are treated. The simpler-directly visible in the signals, which still demand serious methods and algorithms in the feature detection, similarity investigation and classification. The major actions in this domain are of geometric, thus simpler sort, though there are still hard problems related to simple situations. The other large class of less simple signals unsuitable for direct geometric or statistic approach, are signals with interesting frequency components and behavior, those suitable for spectroscopic analysis. Semantics of spectroscopy, spectroscopic structures and research demanded operations and transformations on spectra and time spectra are presented. The both classes of structures and related analysis methods and tools share a large common set of algorithms, all of which aiming to the full automatization. Some of the signal features present in the brain signal patterns are demonstrated, with the contexts relevant in BCI, brain computer interfaces. Mathematical representations, invariants and complete characterization of structures in broad variety of biological signals are in the central focus.

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“…Camphor and other terpenoid compounds do not accumulate in the environment since many soil bacteria like Pseudomonas putida readily degrade these compounds [24]. Although herbal medicines and essential oils have been widely used in folk and modern alternative medicine for many years and have shown to be very effective in curing many symptoms and diseases, the misuse of them can be very harmful for the body causing serious problems [25]. Camphor intoxication has been reported in humans and especially children but mostly because of accidental ingestion or exceeding the recommended amount [3].…”

Section: Dosage and Toxicitymentioning

confidence: 99%

Camphor (Cinnamomum camphora), a traditional remedy with the history of treating several diseases

Hamidpour¹,

Hamidpour²,

Hamidpour³

et al. 2013

IJCRI

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Introduction: The purpose of this literature review is to gain knowledge of the long history, wide variety and extensive applications of camphor, both in traditional and modern medicine. Camphor (Cinnamomum camphora) is obtained from the wood of camphor tree. It has been used for centuries, throughout the world as a remedy for treating variety of symptoms such as inflammation, infection, congestion, pain, irritation, etc. The studies have shown that some of the components of Cinnamomum camphora have suppressive and antimutagenic effect in number of human cancer cells without harming the healthy cells. In this paper our focus is on the use of camphor as a remedy for daily minor problems as well as reporting some information about the new applications of this traditional medicine to treat or prevent some serious lifethreatening diseases sucha as cancer and diabetes. We hope to get the attention of researchers for conducting more studies on the effects of camphor on patients with memory and brain disorders as well.

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Effect of camphor essential oil on rat cerebral cortex activity as manifested by fractal dimension changes

Cited by 10 publications

References 16 publications

Use of the Hurst Exponent for Analysis of Electrocortical Epileptiform Activity Induced in Rats by Administration of Camphor Essential Oil or 1,8-Cineole

Use of the Hurst Exponent for Analysis of Electrocortical Epileptiform Activity Induced in Rats by Administration of Camphor Essential Oil or 1,8-Cineole

Detection of Structural Features in Biological Signals

Camphor (Cinnamomum camphora), a traditional remedy with the history of treating several diseases

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