Effect of cadmium exposure on hepatopancreas and gills of the estuary mud crab ( Scylla paramamosain ): Histopathological changes and expression characterization of stress response genes

Zhu, Qi; Zhou, Zhong Kai; Tu, Dan Dan; Zhou, Yi; Wang, Cong; Liu, Ze Peng; Gu, Wen Bin; Chen, Yu Yin; Miao, Shuying

doi:10.1016/j.aquatox.2017.11.020

Cited by 51 publications

(14 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cadmium toxicity is responsible for affecting cellular and molecular processes, with potential increases in oxidative stress, apoptosis, as well as inhibition of the energy metabolism and molting and histological changes [20]. Zhu et al [20] studied the effect of Cd exposure in crabs (Scylla paramamosain), reporting important histological changes, such as gill lamellae surface wrinkling, which can lead to osmoregulatory dysfunctions, and changes in hepatopancreas nuclei and mitochondrial morphology, which can lead to reduced energy production and compromise animal metabolism [20].…”

Section: Effect Of Metals/potentially Toxic Elements On Crustacean Healthmentioning

confidence: 99%

“…In general, most toxic metals accumulate in crustacean hepatopancreas [18] and gills [19]. The hepatopancreas is the main bioaccumulator organ, due to its xenobiotic detoxification function [10,20], while gills capture and accumulate metals through water due to high a contact surface and thin epithelium [11]. Muscle [21], gonads [22] and carapace [17] may also bioaccumulate metals, to a lesser extent.…”

Section: Introductionmentioning

confidence: 99%

“…The main metals, reported in several toxicity studies on animals, humans, and the environment, are Al, the metalloid As, Cd, Cr, Cu, Pb, Hg, Ni, and Ag [5,16,[23][24][25][26][27]. In the longterm, in animals, the accumulation of these metals whether essential in high concentrations or nonessential, can cause several types of damage, mainly to the respiratory [20,28] and gastrointestinal [29,30] systems, as well as affecting reproductive capacity [31,32] and interfering with animal metabolism [33,34]. In humans, these metals may lead to liver, kidney, central nervous system, mucus tissue, intestinal tract, and reproductive system damage, and are considered a severe public health issue [5].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Systematic Review on Metal Dynamics and Marine Toxicity Risk Assessment Using Crustaceans as Bioindicators

Rodrigues

Ferrari

Kato

et al. 2021

Biol Trace Elem Res

View full text Add to dashboard Cite

Metals, many of which are potentially toxic, are present in the aquatic environment originated from both natural and anthropogenic sources. In these ecosystems, these elements are mostly deposited in the sediment, followed by water dissolution, potentially contaminating resident biota. Among several aquatic animals, crustaceans are considered excellent bioindicators, as they live in close contact with contaminated sediment. The accumulation of metal, whether they are classified as essential, when in excessive quantities or nonessential, not only cause damage to the health of these animals, but also to the man who consumes seafood. Among the main toxic elements to animal and human health are aluminum, arsenic, cadmium, chromium, copper, lead, mercury, nickel and silver. In this context, this systematic review aimed to investigate the dynamics of these metals in water, the main bioaccumulative tissues in crustaceans, the effects of these contaminants on animal and human health, and the regulatory limits for these metals worldwide. A total of 91 articles were selected for this review, and an additional 68 articles not found in the three assessed databases were considered essential and included, totaling 159 articles published between 2010 and 2020. Our results indicate that both chemical speciation and abiotic factors such as pH, oxygen and salinity in aquatic environments affect element bioavailability, dynamics, and toxicity. Among crustaceans, crabs are considered the main bioindicator biological system, with the hepatopancreas appearing as the main bioaccumulator organ. Studies indicate that exposure to these elements may result in nervous, respiratory, and reproductive system effects in both animals and humans. Finally, many studies indicate that the concentrations of these elements in crustaceans intended for human consumption exceed limits established by international organizations, both with regard to seafood metal contents and well as daily, weekly, or monthly intake limits set for humans, indicating consumer health risks.

show abstract

Section: Effect Of Metals/potentially Toxic Elements On Crustacean Healthmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Systematic Review on Metal Dynamics and Marine Toxicity Risk Assessment Using Crustaceans as Bioindicators

Rodrigues

Ferrari

Kato

et al. 2021

Biol Trace Elem Res

View full text Add to dashboard Cite

show abstract

“…It should be durable and remain in one piece for the special water environment and slow eating habit of Chinese mitten crabs (Sitaula, ). In addition, the heavy metals, such as Pb, Cd and Cr, naturally occur in the water environment and diets, which can lead to serious adverse effects in crustaceans (Lu, Yang, Xia, Zong, & Liu, ; Wu, Huang, Chung, & Nan, ; Zhu et al, ).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of palygorskite on pellet quality, growth, antioxidant status and mineral contents of Chinese mitten crabs (Eriocheir sinensis)

Zhang

Cui

et al. 2020

Aquac Res

View full text Add to dashboard Cite

This study evaluated the palygorskite inclusion effects on the pellet quality, growth, antioxidant status and mineral contents of Chinese mitten crabs. Crabs (n = 640; initial average weight, 1.36 ± 0.02 g) were allocated into four groups with eight replicates of twenty crabs. A basal diet supplemented with 0, 10, 20 and 40 g/kg palygorskite was fed to crabs for 8 weeks respectively. Results exhibited that dietary addition of palygorskite enhanced the pellet process electrical energy consumption, improved the hardness and durability (p < .05), reduced percentage of fines and dissolved weight loss of pellets (30, 60, 120, 240, 480 min; p < .05) in the water. Crabs had no differences on the weight gain, specific growth rate, feed conversion ratio, abdominal meat ratio and edible viscera index among the groups (p > .05). Palygorskite inclusion decreased the MDA contents of edible viscera and abdominal meat (p < .05) of Chinese mitten crabs. The ether extract contents of edible viscera in palygorskite inclusion groups were lower than that of the control group (p < .05) in Chinese mitten crabs. Furthermore, palygorskite addition linearly increased the Fe level in the edible viscera and reduced tissue Pb and Cr (p < .05) accumulations of Chinese mitten crabs. In conclusion, palygorskite inclusion could improve pellet quality, enhance the antioxidant capacity and Fe content of edible viscera, decrease the edible viscera ether extract level and tissue Pb and Cr accumulations without impairing the growth performance of Chinese mitten crabs, but increased the electrical energy consumption of pelleting.

show abstract

“…Chitinase activity can be inhibited by cadmium stress (Luo, Pei, Jing, Zou & Wang, ). Furthermore, the morphology and histopathology of the hepatopancreas and gills in Scylla paramamosain were negatively affected by cadmium exposure, which can cause a stress response (Zhu et al., ). The results indicated that chitinase genes were ubiquitously expressed in crustaceans; however, their biological functions and biochemical properties are not well established.…”

Section: Introductionmentioning

confidence: 99%

Seven transcripts from the chitinase gene family of the mud crabScylla paramamosain: Their expression profiles during development and moulting and under environmental stresses

Zhou

et al. 2018

Aquac Res

Self Cite

View full text Add to dashboard Cite

In crustaceans, chitinases (Chts) play crucial roles in physiological functions such as chitinous food digestion, moulting and stress responses. Chitinases have been identified in both prokaryotes and eukaryotes, but the composition and number of Cht family members vary across species, especially in crustaceans. Seven Cht transcripts, all of which contained the conserved enzyme activity motif, were cloned from Scylla paramamosain for the first time, and SpCht1-SpCht6 were clearly classified into groups 1-6, respectively, through phylogenetic analysis. Notably, SpCht7, which had two catalytic domains, was identified for the first time in crabs and crustaceans.Although SpCht7 could not be grouped into any known Cht subclasses, it clustered together with insect Cht7 and could be classified into a novel subclass that we named group 7. The tissue distributions of SpChts, as well as their expression profiles during embryonic and larval development, growth-related moulting, salinity and cadmium stresses, were also investigated. The results suggested that SpChts might have different and varied biological functions. These results would be helpful for understanding and clarifying the roles of chitinases in crab development, moulting and responses to environmental stress. These results also provide new insight into the origin and evolution of the chitinase gene family in crabs and other crustaceans. K E Y W O R D Schitinase, development, moulting, Scylla paramamosain, stress

show abstract

Effect of cadmium exposure on hepatopancreas and gills of the estuary mud crab ( Scylla paramamosain ): Histopathological changes and expression characterization of stress response genes

Cited by 51 publications

References 47 publications

A Systematic Review on Metal Dynamics and Marine Toxicity Risk Assessment Using Crustaceans as Bioindicators

A Systematic Review on Metal Dynamics and Marine Toxicity Risk Assessment Using Crustaceans as Bioindicators

Evaluation of palygorskite on pellet quality, growth, antioxidant status and mineral contents of Chinese mitten crabs (Eriocheir sinensis)

Seven transcripts from the chitinase gene family of the mud crabScylla paramamosain: Their expression profiles during development and moulting and under environmental stresses

Contact Info

Product

Resources

About