Effect of breast-conserving surgery and modified radical mastectomy on quality of life of early breast cancer patients

Abstract

We aimed to explore the clinical efficacy of breast-conserving surgery and modified radical mastectomy on the quality of life (QoL) in patients with early breast cancer. A total of 100 patients treated with breast-conserving surgery (BCS) were recruited in the BCS group, and 100 patients treated with modified radical mastectomy (MRM) in the MRM group. Our results showed that patients had significantly shorter operation time and hospital stay, smaller incisions, and less intraoperative blood loss in the BCS group than in the MRM group. The total complication rate was significantly lower in the BCS. The rate of good-toexcellent aesthetic outcomes in the BCS group was significantly. At one year and three years after surgery, the QoL in the BCS group was significantly higher than that in the MRM group (P<0.0001). In conclusion, BCS is as effective as MRM in early breast cancer, but confers better perioperative and aesthetic outcomes, higher QoL, and lower postoperative complication rate.

Effects of Cirsium setidens extract on gene expression related to apoptosis induction and metastasis inhibition in human breast cancer

“…Breast cancer is one of the three major cancers in women, accounting for 24.2% of cancers in women worldwide. As of 2018, 2.09 million patients were diagnosed with breast cancer, and in Korea, the incidence rate was 59.8 per 100,000 people, one of the highest among Asian countries (Liu & Luo, 2021). Breast cancer is caused by the abnormal proliferation of mammary lobules, which are located in the distal regions of the mammary gland, and of connective tissue cells around them; this is attributable to the exposure to endocrine disruptors (Kim & Lee, 2020).…”