Two field experiments were carried out during the fall seasons of 2014 and 2015 to investigate the main effect of humic acid (0 and 1000 ppm), chitosan (0 and 250 ppm) and NK (0, 25, 50, 75, and 100%) of the recommended rate for the commercial production of potato as well as their various interactions on some vegetative growth characters, tubers yield and its components. The obtained results indicated that increasing the applied level of NK up to 100% constantly increased most of vegetative growth characters (foliage fresh weight, leaf area, plant height, number of main stems and leaf chlorophyll content) and tubers yield and its components (total tuber yield plant -1 and fed -1 and tubers yield of large, medium and small sized plant -1 ). The highest two NK levels (75 and 100 %) didn't, significantly, differ in their effects on most of vegetative traits. Application of humic acid or chitosan produced, significantly, increased growth parameters as well as tubers yield and its components. The most favorable combination treatments that produced the highest mean values of growth and tubers yield as well as yield components were 75 or 100 % NK + humic acid or chitosan, humic acid + chitosan and 75 or 100% NK+ humic acid + chitosan . Therefore, fertilizing potato plants with 75 or 100 % of the recommended dose of NK combined with foliar spray of humic acid and chitosan could be recommended to gain the best results.