Effect of body weight on free fatty acid release by adipose tissuein vitro

Release of Free Fatty Acids from Adipose Tissue <i>in vitro</i> after Adrenalin in Relation to the Total Body Fat in Rats of Different Age and Different Physical Activity

“…Our previous observations in male rats fed ad libitum revealed that daily running on a treadmill when initiated in full-grown animals increased gradually in a manner not to evoke a stress causes that epididymal adipose tissue releases in vitro after addition of different amounts of adrenalin (26) more FFA than adipose tissue of control animals, whereby the running animals have a smaller proportion of body fat (21 b). A similar difference as regards the release of FFA from adipose tissue was found for instance between younger and older animals (1,2,24). We were therefore interested to know, how the influence of enhanced muscular activity (running on a treadmill) begun in early ontogeny will manifest itself in the reactibility of adipose tissue to adrenaline either before the termination of 44 P arizkova and Stankova growth, or in full-grown animals, and what is the relationship of the release of FFA in vitro to the total ratio of body fat during growth, adult and old age.…”

“…In conjunction with this attention was also paid to the ability of adipose tissue to relase FFA in vitro (10b). Investi gations were made in animals of different age (1,2,24), fed different diets or in fasting animals (23), in animals with normal body-weight or obese ones (16,6), after adaptation to cold (11) or increased physical activity (20, 21a, 6). Our previous observations in male rats fed ad libitum revealed that daily running on a treadmill when initiated in full-grown animals increased gradually in a manner not to evoke a stress causes that epididymal adipose tissue releases in vitro after addition of different amounts of adrenalin (26) more FFA than adipose tissue of control animals, whereby the running animals have a smaller proportion of body fat (21 b).…”

The Effect of Epinephrine on Fat Metabolism in Old Rats

“…During the print of our paper, a work of Altschuler (Altschuler et al, 1962) has been published. In agreement with our results the authors found that the release of NEFA from epididym.…”

Influence of physical activity on a treadmill on the metabolism of adipose tissue in rats

“…The release of NEFA from adipose tissue in vitro (Gordon & Cherkes, 1958; Reichl, 1959) and the effect of catecholamines on this process (White & Engel, 1958; Wenke, Muhlbachovh & Hynie, 1962) in various physiological conditions has been demonstrated, e.g. after fasting in normal rats (Robinson, 1960), after fasting in obese hyperglycaemic and lean mice (Marshall & Engel, 1960), in young and old rats (Benjamin, Gellhorn, Wagner & Kundel, 1961 ; Altschuler, Lieberson & Spitzer, 1962;Tenorovh & Hrbza, 1962), and after cold acclimatization (Hannon & Larson, 1962). We have therefore explored the problem whether, in conjunction with changes in the proportion of adipose tissue and other indicators suggesting adaptation to a more intense muscular activity, reactivity of adipose tissue to adrenaline is also affected.…”