The flexural properties in the longitudinal direction for natural and thermo-hydromechanically densified Moso bamboo (Phyllostachys pubescens Mazel) culm wall material are measured. The modulus of elasticity (MOE) and modulus of rupture (MOR) increase with densification, but at the same density, the natural material is stiffer and stronger than the densified material. This observation is primarily attributed to bamboo's heterogeneous structure and the role of the parenchyma in densification. The MOE and MOR of both the natural and densified bamboo appear linearly related to density. Simple models are developed to predict the flexural properties of natural bamboo. The structure of the densified bamboo is modelled, assuming no densification of bamboo fibers, and the flexural properties of densified bamboo are then predicted using this structure and the same cell wall properties of that of the natural material modelling. The results are then compared with those for two analogous structural bamboo products: Moso bamboo glulam and scrimber.