Effect of blackcurrant-, cranberry- and plum juice consumption on risk factors associated with kidney stone formation

Keßler, Torsten; Jansen, Brigitte; Hesse, Albrecht

doi:10.1038/sj.ejcn.1601442

Cited by 95 publications

(62 citation statements)

References 19 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This elevation of dietary acidity has recently been reproduced for cranberry and in part for plum ingestion [21]. The authors found a significant fall in urine pH only after cranberry juice, but not after plum juice ingestion [21] which can be explained by a lower dietary PRAL (higher alkalizing potential) of plums compared to cranberries.…”

Section: Consequences For the Estimation Of Net Endogenous Acid Produmentioning

confidence: 79%

Acid Base Considerations in Stone-Age Farming Sweet Potato Eaters, Modern-Day Sweet Potato Eaters, and High-Protein Consumers

Berkemeyer¹,

Manz²

2008

TONUTRJ

View full text Add to dashboard Cite

Net endogenous acid production (NEAP) can be estimated by a primarily anthropometry-dependent organic acid anion (OA) component and the particularly diet-dependent potential renal acid load (PRAL). However, there is evidence that certain foods may also impact on the OA component. Here, we discuss measurements of urinary 24-h OA excretion obtained in healthy subjects, against the background of relevant literature with a special focus on former Papuan New Guinea stone-age farmers eating predominantly highland sweet potatoes. Contrary to the reports in Papuans, we observed only modest increases of 5-12% in 24-h excretion rates of OAs (including the detoxification product of phenolic and benzoic acids, i.e., hippuric acid) in healthy adults consuming commonly available yellow-fleshed sweet potatoes. This and additional results on OA increases after higher protein intakes suggest that a specification of the NEAP=PRAL+OA model for estimating the diet-dependent acid load to the metabolic system might be useful regarding particular foods and their effects on the OA component.

show abstract

Section: Consequences For the Estimation Of Net Endogenous Acid Produmentioning

confidence: 79%

Acid Base Considerations in Stone-Age Farming Sweet Potato Eaters, Modern-Day Sweet Potato Eaters, and High-Protein Consumers

Berkemeyer¹,

Manz²

2008

TONUTRJ

View full text Add to dashboard Cite

show abstract

“…Unsweetened blackcurrant diluted juice increased urinary citrate by 25% over baseline (Kessler et al 2002 experimental M) (23). The consumption of a non citrus alkaline fruit (melon) also has a positive effect in increasing citraturia as compared to citrus fruit consumption (Baia et al 2012 experimental M) (24).…”

Section: Non Citrus Juicesmentioning

confidence: 99%

Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group

Prezioso

Strazzullo

Lotti

et al. 2015

Arch Ital Urol Androl

159

View full text Add to dashboard Cite

Objective: Diet interventions may reduce the risk of urinary stone formation and its recurrence, but there is no conclusive consensus in the literature regarding the effectiveness of dietary interventions and recommendations about specific diets for patients with urinary calculi. The aim of this study was to review the studies reporting the effects of different dietary interventions for the modification of urinary risk factors in patients with urinary stone disease. Materials and Methods: A systematic search of the Pubmed database literature up to July 1, 2014 for studies on dietary treatment of urinary risk factors for urinary stone formation was conducted according to a methodology developed a priori. Studies were screened by titles and abstracts for eligibility. Data were extracted using a standardized form and the quality of evidence was assessed. Results: Evidence from the selected studies were used to form evidencebased guideline statements. In the absence of sufficient evidence, additional statements were developed as expert opinions. Conclusions: General measures: Each patient with nephrolithiasis should undertake appropriate evaluation according to the knowledge of the calculus composition. Regardless of the underlying cause of the stone disease, a mainstay of conservative management is the forced increase in fluid intake to achieve a daily urine output of 2 liters. Hypercalciuria: Dietary calcium restriction is not recommended for stone formers with nephrolithiasis. Diets with a calcium content ≥ 1 g/day (and low protein-low sodium) could be protective against the risk of stone formation in hypercalciuric stone forming adults. Moderate dietary salt restriction is useful in limiting urinary calcium excretion and thus may be helpful for primary and secondary prevention of nephrolithiasis. A low-normal protein intake decrease calciuria and could be useful in stone prevention and preservation of bone mass. Omega-3 fatty acids and bran of different origin decreases calciuria, but their impact on the urinary stone risk profile is uncertain. Sports beverage do not affect the urinary stone risk profile. Hyperoxaluria: A diet low in oxalate and/or a calcium intake normal to high (800-1200 mg/day for adults) reduce the urinary excretion of oxalate, conversely a diet rich in oxalates and/or a diet low in calcium increase urinary oxalate. A restriction in protein intake may reduce the urinary excretion of oxalate although a vegetarian diet may lead to an increase in urinary oxalate. Adding bran to a diet low in oxalate cancels its effect of reducing urinary oxalate. Conversely, the addition of supplements of fruit and vegetables to a mixed diet does not involve an increased excretion of oxalate in the urine. The intake of pyridoxine reduces the excretion of oxalate. Hyperuricosuria: In patients with renal calcium stones SummaryNo conflict of interest declared. DOI: 10.4081/aiua.2015.2.105the decrease of the urinary excretion of uric acid after restriction of dietary protein and purine is suggested although not cle...

show abstract

“…Fruits and fruit juices with high citrate content generally are assumed to deliver an alkali load. However, previously published studies on the influence of different citrate-rich fruit juices/beverages on the risk for stone formation have provided conflicting results, with some beverages decreasing the risk for stones whereas others have either no effect or increase the risk (7)(8)(9)(10)(11)(12)(13)(14)(15)(16). One reason might be the different constituents of various beverages.…”

mentioning

confidence: 77%

Comparative Value of Orange Juice versus Lemonade in Reducing Stone-Forming Risk

Odvina

2006

Clinical Journal of the American Society of Nephrology

126

View full text Add to dashboard Cite

Foods that are high in citrate content generally are assumed to deliver alkali load when consumed irrespective of the accompanying cation. The object of this randomized, crossover study was to compare the effects of orange juice with those of lemonade on acid-base profile and urinary stone risks under controlled metabolic conditions. Thirteen volunteers (nine healthy subjects and four stone formers) sequentially received distilled water, orange juice, or lemonade while on constant metabolic diet. Twenty-four-hour urine samples were collected for acid-base parameters and stone risk analysis. Orange juice but not lemonade provided alkali as evidenced by higher net gastrointestinal alkali absorption and higher urinary pH and citrate compared with control. Urinary calcium was not significantly different, but urinary oxalate was higher during the orange juice phase. The calculated supersaturation of calcium oxalate was lower in the orange juice phase compared with control. Calculated undissociated uric acid was lower in the orange juice phase compared with both control and lemonade phases. The calculated supersaturation of brushite was significantly higher in the orange juice phase compared with both control and lemonade phases. Despite comparable citrate content, this study showed that orange juice has greater alkalinizing and citraturic effects than lemonade. Consumption of orange juice was associated with lower calculated calcium oxalate supersaturation and lower calculated undissociated uric acid. This short-term study suggests that orange juice consumption could result in biochemical modification of stone risk factors; however, additional studies are needed to evaluate its role in long-term prevention of recurrent nephrolithiasis.Clin J Am Soc Nephrol 1: 1269 -1274, 2006. doi: 10.2215/CJN.00800306 M anagement of recurrent kidney stones requires both diet/lifestyle modification and medical therapy, and one of the important elements of medical therapy is the administration of potassium alkali such as potassium citrate. Potassium citrate has been shown to decrease stone formation rate in patients with idiopathic hypocitraturic calcium nephrolithiasis (1,2), hyperuricosuric (3), and thiazideunresponsive patients (4). Potassium citrate is believed to exert its beneficial effect through its citraturic and urinary alkalinizing actions. The increase in urinary citrate retards spontaneous nucleation and agglomeration of calcium oxalate crystals (5). Moreover, by increasing urinary pH and decreasing urinary content of undissociated uric acid, this treatment is useful in preventing uric acid stones (6).There are patients who are not able to tolerate potassium citrate, however, because of gastrointestinal adverse effects. Some may prefer nonpharmacologic therapy. In such cases, dietary sources of citrate may be considered an option or alternative to pharmacologic agents. Fruits and fruit juices with high citrate content generally are assumed to deliver an alkali load. However, previously published studies on the influence o...

show abstract

Effect of blackcurrant-, cranberry- and plum juice consumption on risk factors associated with kidney stone formation

Cited by 95 publications

References 19 publications

Acid Base Considerations in Stone-Age Farming Sweet Potato Eaters, Modern-Day Sweet Potato Eaters, and High-Protein Consumers

Acid Base Considerations in Stone-Age Farming Sweet Potato Eaters, Modern-Day Sweet Potato Eaters, and High-Protein Consumers

Dietary treatment of urinary risk factors for renal stone formation. A review of CLU Working Group

Comparative Value of Orange Juice versus Lemonade in Reducing Stone-Forming Risk

Contact Info

Product

Resources

About