Effect of bisphosphonate treatment on the jawbone: an exploratory study using periapical and panoramic radiographic evaluation

Barngkgei, Imad; Halboub, Esam; Almashraqi, Abeer A

doi:10.1007/s11282-018-0358-4

Cited by 19 publications

(14 citation statements)

References 48 publications

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“…Bone trabeculation can be assessed by several means ranging from the periapical radiographs up to the multispiral computed tomography [29]. The more sensitive measurement is the bone mineral density which can be accurately measured using CT; but it is costly in terms of radiation exposure, so the other alternative is the use of CBCT; the connection between HU and CBCT values is high when measured bone density at the impacted and erupted canine [30].…”

Section: Discussionmentioning

confidence: 99%

Qualitative and quantitative three-dimensional evaluation of maxillary basal and dentoalveolar dimensions in patients with and without maxillary impacted canines

et al. 2022

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Background This study aimed to three-dimensionally evaluate the qualitative and quantitative maxillary basal, dentoalveolar, and dental dimensions in patients with unilateral or bilateral maxillary impacted canines relative to their normal peers. Materials and methods This is a retrospective comparative study. Cone-beam computed tomography images of one hundred and fifty adult patients were divided into three equal groups: unilateral, bilateral, and control groups. Each had 50 patients that were three-dimensionally analysed. The quantitative measurements involved three basal (molar basal width, premolar basal width, and arch depth), seven dentoalveolar (molar alveolar width, premolar alveolar width, inter-molar width, inter-premolar width, inter-canine width, arch length, and arch perimeter), and two dental (canine length and width) measurements. The qualitative measurements included four bone density areas (buccal, lingual, mesial, and distal) around the maxillary impacted canines. Result Differences between the three groups were statistically different for the quantitative measurements involving the two basal variables (molar basal width and premolar basal width) and all measured dentoalveolar variables; these were smaller in the unilateral and bilateral groups compared with the control group (p < 0.001). Unilateral and bilateral impacted canine groups showed significantly wider and shorter canines than the control group (p < 0.001). The qualitative measurements (the four bone density areas) around unilateral and bilateral impacted canine groups showed significantly greater density than the control group (p < 0.001). There was no significant qualitative or quantitative difference between the unilateral and bilateral impacted canines. The three groups had no significant variations in terms of arch depth. Conclusion Maxillary unilateral and bilateral canine impactions are associated with reduced basal and dentoalveolar dimensions as well as wider and shorter maxillary canines compared to normal peers. The quality of bone around unilateral and bilateral impacted maxillary canines is higher than in non-impacted cases. Unilateral and bilateral canine impactions have quite similar qualitative and quantitative parameters.

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Section: Discussionmentioning

confidence: 99%

Qualitative and quantitative three-dimensional evaluation of maxillary basal and dentoalveolar dimensions in patients with and without maxillary impacted canines

et al. 2022

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“…Bulgularımız, literatür sonuçlarıyla uyumludur. 18,19,27,32 İÇKON'ye dair bazı görüntü bulguları, osteoradyonekroz, osteomiyelit, kemik metastazları gibi diğer kemik hastalıklarına büyük benzerlik gösterebilir, bu yüzden mevcut hastalıkla ilgili detaylı anamnez ve klinik muayene doğru teşhis ve tedavi planı için gereklidir.…”

Section: Discussionunclassified

Radiographic Findings in Patients Using Antiresorptive Agents: Retrospective Assessment: Cross-Sectional Study

AKBULUT¹

2022

Turkiye Klinikleri J Dental Sci

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İlaçlara bağlı olarak gelişen çene kemiği osteonekrozu (İÇKON), oral ve maksillofasiyal bölgede antirezorptif veya antianjiyogenik ajanların sebep olduğu ciddi oral komplikasyonlardandır. Antirezorptif ajanlar; bifosfonatlar, reseptör aktivatör nükleer fak-tör kappa-B ligand (RANKL) monoklonal antikorları, östrojen, selektif östrojen reseptör modülatörleri ve kalsitonin gibi ilaçlardır. Bunlar arasında bifosfonatlar ve denosumab, İÇKON'ye sebep olduğu kanıtlanmış ajanlardır. [1][2][3][4][5][6][7]

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“…Quantitative trabecular and cortical bone measurements have shown to be potentially useful tools in detecting bone changes caused by bisphosphonates in mixed populations of patients taking oral or intravenous bisphosphonate (39,40). In the studies, which evaluated only patients taking oral bisphosphonates for osteoporosis, radiographic and cone-beam computed tomography measurements were not predictive of MRONJ (41,42).…”

Section: Predictive Factors For Mronjmentioning

confidence: 99%

Prevention and treatment of oral adverse effects of antiresorptive medications for osteoporosis – A position paper of the Brazilian Society of Endocrinology and Metabolism (SBEM), Brazilian Society of Stomatology and Oral Pathology (Sobep), and Brazilian Association for Bone Evaluation and Osteometabolism (Abrasso)

Madeira¹,

Rocha²,

Moreira³

et al. 2020

Archives of Endocrinology and Metabolism

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Antiresorptive therapy is the main form of prevention of osteoporotic or fragility fractures. Medicationrelated osteonecrosis of the jaw (MRONJ) is a relatively rare but severe adverse reaction to antiresorptive and antiangiogenic drugs. Physicians and dentists caring for patients taking these drugs and requiring invasive procedures face a difficult decision because of the potential risk of MRONJ. The aim of this study was to discuss the risk factors for the development of MRONJ and prevention of this complication in patients with osteoporosis taking antiresorptive drugs and requiring invasive dental treatment. For this goal, a task force with representatives from three professional associations was appointed to review the pertinent literature and discuss systemic and local risk factors, prevention of MRONJ in patients with osteoporosis, and management of established MRONJ. Although scarce evidence links the use of antiresorptive agents in the context of osteoporosis to the development of MRONJ, these agents are considered a risk factor for this complication. Despite the rare reports of MRONJ in patients with osteoporosis, the severity of symptoms and impact of MRONJ in the patients' quality of life make it imperative for health care professionals to consider this complication when planning invasive dental procedures.

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Effect of bisphosphonate treatment on the jawbone: an exploratory study using periapical and panoramic radiographic evaluation

Cited by 19 publications

References 48 publications

Qualitative and quantitative three-dimensional evaluation of maxillary basal and dentoalveolar dimensions in patients with and without maxillary impacted canines

Qualitative and quantitative three-dimensional evaluation of maxillary basal and dentoalveolar dimensions in patients with and without maxillary impacted canines

Radiographic Findings in Patients Using Antiresorptive Agents: Retrospective Assessment: Cross-Sectional Study

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