Effect of biliopancreatic loop length mini gastric bypass on metabolic disorders resolution and nutritional deficiency

Abstract

Recently, the International Federation of Obesity Surgery (IFSO) has recognized gastric bypass surgery as one of the major bariatric / metabolic surgeries. However, the issue of nutritional deficiency after mini-shunting, which leads to repeated surgical interventions for deficient states, remains debatable. Efforts to balance the loss of excess body weight, compensation for concomitant metabolic disorders and nutritional insufficiency make the issue of the “ideal” length of the biopancreatic loop relevant. Therefore, the purpose of the study was to compare the bariatric and metabolic effects of mini-shunting of the stomach depending on the length of the biliary pancreatic loop. The study included 42 patients (24 women (57.1%) and 18 men (42.9%)), aged 24 to 65 years, with a body mass index (BMI) of 40 kg / m2 and above, with a mini-gastric bypass with minimally invasive access. The operation consisted of forming a long gastric reservoir along the small curvature of the stomach with the imposition of a semi-manual anastomosis with a loop of the small intestine 200–250 cm from the ligament of the Trinity. The length of the biopancreatic loop was selected according to the body mass index (200 cm — <45 kg / m2 (23 patients), 250+ cm — ˃45 kg / m2 (15 patients)) and the nature of the concomitant metabolic disorders. Anthropometric, laboratory and instrumental research methods were used. The level of HbA1c and the level of triglycerides were determined. The results were evaluated at 1, 3, 6, 9 and 12 months after surgery. Statistical processing of data was performed using StatPlus 6 Profesional. Postoperative complications were diagnosed in 3 (7.2%) patients. An early complication of Twisted pouch, which required repeated surgery, was observed in 1 (2.4%) patient. Late complications (peptic ulcer of gastroenteroanastomosis and insufficient weight loss) were found in 2 (4.8%) patients. The average percentage of excess body weight loss in the 200 cm and 250 cm group was 70.1 ± 0.8% and 71.8 ± 0.6% (p>0.05), respectively; type 2 diabetes mellitus was diagnosed in 5 (83.3%) and 7 (87.5%) patients, respectively; dyslipidemia compensation was achieved in 3 (50%) and 5 (71.4%) patients, respectively; hypocalcaemia was detected in 1 (12.5%) and 3 (27.3%) patients, respectively; decreased levels of iron were diagnosed in 1 (12.5%) and 2 (18.2%) patients, respectively. Thus, the results obtained indicate that as the length of the loop increases, the metabolic effect increases, but the risk of electrolyte exchange disorders may increase.