Effect of berberine alkaloids on Bifidobacterium adolescentis growth by microcalorimetry

Yan, Dan; Han, Ying; Wei, Li; Xiao, Xincai

doi:10.1007/s10973-008-9273-y

Cited by 14 publications

(4 citation statements)

References 14 publications

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“…Microcalorimetry can also reveal temporal details (such as thermal effect) that are not observable by other techniques (Batovska et al, 2007;Leng et al, 2007;Kwon et al, 2008). It has already been demonstrated that calorimetric methods can be used for fundamental studies of organisms' growth (von Ah et al, 2008;Yan et al, 2009b). Accordingly, microcalorimetry is a good method for evaluating the antibacterial activities of R. coptidis.…”

Section: Original Articlementioning

confidence: 99%

Applications of microcalorimetry in the antibacterial activity evaluation of variousRhizoma coptidis

Feng¹,

Yan²,

Zhao³

et al. 2011

Pharmaceutical Biology

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Section: Original Articlementioning

confidence: 99%

Applications of microcalorimetry in the antibacterial activity evaluation of variousRhizoma coptidis

Feng¹,

Yan²,

Zhao³

et al. 2011

Pharmaceutical Biology

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“…Rhizoma coptidis (Huanglian in Chinese) (R. coptidis) is a strong and efficacious antibacterial, anti-inflammatory, detoxicant, and antiviral material that is also effective in removing toxicosis and dispelling dampness [14][15][16][17]. The antibacterial activity of this herb represents its most pronounced pharmacological effect.…”

mentioning

confidence: 99%

A quality evaluation strategy for Rhizoma coptidis from a variety of different sources using chromatographic fingerprinting combined with biological fingerprinting

Yan

Xiong

et al. 2013

Chin. Sci. Bull.

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Most of herbal medicines of different sources are used for the same treatment goal in clinic despite their tremendous differences of the quality. Because the clinical efficacy is closely related to the quality of medicines, the implementation of an effective quality control (QC) process is vital. Chemical methods based on content determination and chromatographic fingerprints (CFs) have been recommended as powerful tools. In spite of advances in QC, it is still difficult to determine that which of the chemical compositions can best reflect the correlation with the desired biological activity. Herein, we have focused on the biological activities of multi-source herbal medicines to establish an analytical method. By looking for correlations between the biological activities and their chemical compositions, the method can identify reasonable chemical indicators or chemical methods with biological activity information. In this study, high-performance liquid chromatography (HPLC) and microcalorimetry are combined as a useful method for evaluating the quality of Rhizoma coptidis from different sources. The results of biological fingerprints (BFs) showed that the antibacterial activity sequence of R. coptidis of different sources was Coptis teeta Wall. (CT)>Coptis chinensis Franch. (CC)>Coptis deltoidea C.Y. Cheng et Hsiao (CD). The "spectrum-activity" relationships between CFs and BFs were investigated using the canonical correlation analysis (CCA). Compared with the CCA result of CFs and BFs, the canonical correlation coefficient r 1 and r 2 were 0.9974 and 0.9752, respectively. It revealed that there are a close correlation between the spectrum-activity relationships and several of the major anti-bacterial components in the CFs, including jatrorrhizine, coptisine, palmatine, and berberine. Of course, R. coptidis was only a representative of multisource medical plants. The result of the current study will provide an effective reference for evaluating the quality of multisource herbal medicines.Rhizoma coptidis, multi-source medical plants, quality control, chromatographic fingerprint, biological fingerprint Citation:Li J X, Yan D, Ma L N, et al. A quality evaluation strategy for Rhizoma coptidis from a variety of different sources using chromatographic fingerprinting combined with biological fingerprinting.

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“…Thus, these resistant bacterial strains showed higher tolerance than C. albicans . Yan [24] studied the inhibitory effects of BBR alkaloids on Bifidobacterium adolescentis . The results showed that the half inhibition concentration (IC50) of BBR on Bifidobacterium adolescentis was 790.3 μg mL −1 .…”

Section: Discussionmentioning

confidence: 99%

Isolation and Characterization of a Bacterial Strain Capable of Efficient Berberine Degradation

Liu

Zhang

Zeng

et al. 2019

IJERPH

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Background: Berberine (BBR) is a pharmaceutical chemical with a broad antibacterial spectrum, and its biological treatment has been of research and practical interest. In this study, a pure bacterial strain B16 was isolated from the activated sludge in a pharmaceutical wastewater treatment plant. The aim of the study is to characterize the properties of the strain B16, especially its BBR degradation capability. Methods: The identification of strain B16 was conducted by visual observation, as well as biochemical and phylogenetic analysis. The degradation kinetics of strain B16 was tentatively described by Haldane model. Results: The strain B16 was 100% determined as a Sphingopyxis sp. The kinetic parameters of BBR degradation by strain B16 were as follows: Vmax 54.73 ± 5.54 mg (g MLSS · h)−1, Km 66.68 ± 8.95 mg L−1, and Ki 43.16 ± 5.92 mg L−1, with an R2 of 0.996. Stain B16 exhibited considerable capability of BBR degradation. BBR of initial concentration 40 mg L−1 could be completely degraded in 48 h under optimal conditions. Conclusions: strain B16 was the first pure culture found with the ability to totally mineralize BBR, indicating the potential of B16 application in real industrial processes.

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Effect of berberine alkaloids on Bifidobacterium adolescentis growth by microcalorimetry

Cited by 14 publications

References 14 publications

Applications of microcalorimetry in the antibacterial activity evaluation of variousRhizoma coptidis

Applications of microcalorimetry in the antibacterial activity evaluation of variousRhizoma coptidis

A quality evaluation strategy for Rhizoma coptidis from a variety of different sources using chromatographic fingerprinting combined with biological fingerprinting

Isolation and Characterization of a Bacterial Strain Capable of Efficient Berberine Degradation

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