2015
DOI: 10.1016/j.etp.2015.05.001
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Effect of Balanites aegyptiaca on Ehrlich Ascitic carcinoma growth and metastasis in Swiss mice

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Cited by 10 publications
(8 citation statements)
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“…In vivo saponin prolonged the survival time of mice bearing murine L1210 leukemia grafts exactly as vincristine [3], which is in good agreements with present finding where methanol fraction displayed remarkable in vitro cytotoxic effect against lymphoblastic leukemia (1301) cell line. Moreover, the current data illustrated powerful cytotoxicity of both Balanites extracts against liver carcinoma which is in conformity with reports recorded that Balanites suppressed Ehrlich ascetic tumors invaded/or affected mice liver and spleen [44]. Cytotoxic activity could also be related to quercetin glycosides present in the methanol extract.…”
Section: Discussionsupporting
confidence: 73%
“…In vivo saponin prolonged the survival time of mice bearing murine L1210 leukemia grafts exactly as vincristine [3], which is in good agreements with present finding where methanol fraction displayed remarkable in vitro cytotoxic effect against lymphoblastic leukemia (1301) cell line. Moreover, the current data illustrated powerful cytotoxicity of both Balanites extracts against liver carcinoma which is in conformity with reports recorded that Balanites suppressed Ehrlich ascetic tumors invaded/or affected mice liver and spleen [44]. Cytotoxic activity could also be related to quercetin glycosides present in the methanol extract.…”
Section: Discussionsupporting
confidence: 73%
“…On the contrary to G1 and G3 animals, G2 (infected-BAF-EE-treated) and G4 (BAF-EEtreated only) goats revealed significant elevation in GPx activity which could be attributed to the BAF-EE antioxidant effect [9,71]. Antioxidant enzymes superoxide dismutase and catalase were elevated in mice treated with different parts of B. aegyptiaca extracts [72]. Phenolic and flavonoid contents of B. aegyptiaca were found to be responsible for its antioxidant effect [9,73].…”
Section: Discussionmentioning
confidence: 92%
“…(2017) ; Hassan et al. (2016) ; Saleh and Emara (2016) ; Issa et al. (2015) breast, lung, skin B. rufescens Garbi et al.…”
Section: Resultsmentioning
confidence: 99%