Effect of aquatic and alcoholic extracts Nigella sativa seeds on liver and kidney functions and efficacy in the blood of males albino rats

Abstract

The study carried out to investigate the effect of orally feeding from each Nigella sativa aqueous and alcoholic extracts at 50 and 100 mg/kg concentration of animal body weight liver and kidney functions parameters in male rats for 21 days. Randomly divided in to (5) groups, each group included (5) animals..The results showed a significant decrease (p<0.05) in Urea, ALP, ALT and AST. led to a significant increase (p<0.05) in total protein, albumin, globulin with the increased concentration of extract, when compared with values in control group. The study concluded that, the aquatic and alcoholic extracts Nigella sativa seeds did not give any effects toxicity on liver and kidney functions in male rats.