Effect of anodal tDCS on human prefrontal cortex observed by fNIRS

Bhutta, M. Raheel; Woo, Seongwoo; Khan, Muhammad Jawad; Hong, Keum–Shik

doi:10.1109/biorob.2016.7523752

Cited by 7 publications

(6 citation statements)

References 45 publications

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“…Among all studies, a general tendency for tDCS to increase HbO 2 was observed. This was consistent across all three studies applying PFC stimulation, 50,56,57 all of which recorded fNIRS activation within the same region as stimulation. Two of these 56,57 applied 1-mA bilateral PFC stimulation (anode left PFC, Fp1 and cathode right PFC, Fp2) and demonstrated a peak in HbO 2 in the bilateral PFC region ∼4 min after the end of stimulation before returning to baseline levels.…”

Section: Prefrontal Stimulationsupporting

confidence: 74%

“…At rest, tDCS was observed to increase cortical activation while task-evoked responses tended toward reduced activation during online stimulation and increased activation following stimulation. At rest, tDCS was observed to be associated with increases in cortical HbO 2 change particularly when responses were captured in close proximity to the site of anodal stimulation, [49][50][51]56,57 Stephens and Berryhill, 2016 59 2…”

Section: Discussionmentioning

confidence: 99%

“…Combining tDCS electrodes with fNIRS optodes over the same scalp location presents researchers with a practical challenge of costimulation with hemodynamic data acquisition. Some studies avoid this difficulty altogether by avoiding concurrent stimulation and fNIRS monitoring, [56][57][58][59][60][61][62][63] as shown in Fig. 4.…”

Section: Technical Considerations Of Combined Fnirs and Tdcsmentioning

confidence: 99%

“…A total of nine studies investigated changes in cortical hemodynamics following tDCS to the cerebral cortex of healthy individuals at rest using fNIRS ( Table 2). The rest period was reasonably standardized across six studies 49,50,56,57,64,65 placing the subject in a seated position. Two studies asked subjects to keep their eyes closed 69,70 and two studies to keep eyes open.…”

Section: Fnirs Responses In the Healthy Population At Restmentioning

confidence: 99%

“…HHb was only analyzed in one study demonstrating a decrease in HHb alongside the increase in HbO 2 in the bilateral PFC region. 57 Notably, HHb was not analyzed in the remaining two studies 50,56 due to a "lack of effect," presumably as no significant changes in HHb were observed.…”

Section: Prefrontal Stimulationmentioning

confidence: 99%

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Systematic review of combined functional near-infrared spectroscopy and transcranial direct-current stimulation studies

et al. 2020

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Significance: Combining transcranial direct-current stimulation (tDCS) with functional nearinfrared spectroscopy (fNIRS) is a recent approach to exploring brain activation evoked by neurostimulation. Aim: To critically evaluate studies combining tDCS and fNIRS and provide a consolidated overview of cortical hemodynamic responses to neurostimulation. Approach: Key terms were searched in three databases (MEDLINE, EMBASE, and PsycINFO) with cross-referencing and works from Google Scholar also evaluated. All studies reporting on fNIRS-derived hemoglobin changes evoked by tDCS were included. Results: Literature searches revealed 474 articles, of which 28 were included for final review (22 in healthy individuals: 9 involving rest and 13 with tasks; 6 in the clinical setting). At rest, an overall increase in cortical activation was observed in fNIRS responses at the site of stimulation, with evidence suggesting nonstimulated brain regions are also similarly affected. Conversely, during tasks, reduced cortical activation was observed during online stimulation. Offline and poststimulation effects were less consistent, as is the impact on clinical populations and their symptom correlation. Conclusion: This review explores the methodological frameworks for fNIRS-tDCS evaluations and summarizes hemodynamic responses associated with tDCS in all populations. Our findings provide further evidence of the impact of tDCS on neuronal activation within functionally connected networks.

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Section: Prefrontal Stimulationsupporting

confidence: 74%