Effect of angiotensin receptor neprilysin inhibitor on physical activity in patients with heart failure with reduced ejection fraction, monitored by implantable electronic device home monitoring
Ina Volis,
Maria Postnikov,
Anat Reiner-Benaim
et al.
Abstract:Aims
Angiotensin receptor neprilysin inhibitor (ARNI) therapy is a cornerstone in the treatment of heart failure with reduced ejection fraction (HFrEF), with significant improvement in mortality as well as morbidity and quality of life. However, maximal ARNI doses often result in hypotension. Recent studies with ‘real world’ experience suggest that lower doses of ARNI are as effective as higher doses.
In order to evaluate the symptomatic effect of low-dose ARNI in HFrEF patients, we ana… Show more
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