Effect of an intravenous single dose of ketamine on postoperative pain in tonsillectomy patients

Abstract

The use of a single small dose of ketamine in a pediatric population undergoing tonsillectomy could reduce the frequency or even avoid the use of rescue analgesia in the postoperative period independent of whether used before or after the surgical procedure.

Something new about ketamine for pediatric anesthesia?

“…There are, however, no large epidemiologic studies in this population. Ketamine produces some kind of analgesia in children [39,40 ]. There is, however, no study designed to evaluate the development of secondary hyperalgesia and the efficacy of ketamine in this population [41].…”

Effects of perioperative intravenous low dose of ketamine on postoperative analgesia in children

“…Ketamine reduced both morphine consumption and pain scores in several studies [4][5][6][7][8][9][10][11][12][13]. There are only a few studies in the paediatric population with conflicting results [14][15][16][17]. The aim of this randomized, prospective, double-blinded, placebo-controlled study was therefore to determine whether intraoperative and postoperative low-dose ketamine reduces postoperative pain scores in children.…”

The effect of preoperative fasting on postoperative pain, nausea and vomiting in pediatric ambulatory tonsillectomy

“…Pre and postoperative medications [7,8], local anesthetics [9,10], antibiotics [11], surgical techniques [12], postoperative pain management [13][14][15]1,16] and also non-pharmacological methods [17,18] have been studied. However, the issue of posttonsillectomy pain has not been satisfactory totally solved [19,20,9], and to the best of our knowledge, the effect of active preoperative nutrition on posttonsillectomy pain has not been studied.…”