Effect of amygdalin on oral cancer cell line: An in vitro study

Sweet almond (Prunus dulcis (Mill.) D.A.Webb) is a known nut, which has long been used in several ethnomedical systems, especially in Persian medicine (PM) for its nutritional and therapeutic activities. In this study, we aimed to provide a summary on traditional uses, phytochemistry, and pharmacological activities of sweet almond.Thus, we reviewed textbooks of PM and electronic literature on traditional medicine.Moreover, the available data on the usage of sweet almond were searched in electronic databases to find articles on its pharmacological properties and phytochemistry. According to phytochemical investigations, this plant contains macronutrients, micronutrients, essential oils, various phenolic compounds, and phytosterols. Current pharmacological studies represent that Prunus dulcis has several biological activities including prebiotic, antimicrobial, antioxidant, antiinflammatory, anticancer, hepatoprotective, cardiometabolic protection, nootropic, anxiolytic, sedative-hypnotic, and nervous-improving effects. Further clinical trials and meta-analysis are required to draw a definitive conclusion on the efficacy and therapeutic activities of almond.

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Almond as a nutraceutical and therapeutic agent in Persian medicine and modern phytotherapy: A narrative review

Karimi

Firouzi

Dadmehr

et al. 2020

Phytotherapy Research

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The potential of apricot seed and oil as functional food: Composition, biological properties, health benefits & safety

Siddiqui

Anwar

Yunusa³

et al. 2023

Food Bioscience

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Amygdalin - A pharmacological and toxicological review

Wang

et al. 2020

Journal of Ethnopharmacology

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Effect of amygdalin on oral cancer cell line: An in vitro study

Cited by 21 publications

References 19 publications

Almond as a nutraceutical and therapeutic agent in Persian medicine and modern phytotherapy: A narrative review

Almond as a nutraceutical and therapeutic agent in Persian medicine and modern phytotherapy: A narrative review

The potential of apricot seed and oil as functional food: Composition, biological properties, health benefits & safety

Amygdalin - A pharmacological and toxicological review

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