Effect of amphiphilic environment on the solution structure of mouse TSPO translocator protein

Analysis and modeling of SDS and DPC micelle SAXS data for membrane protein solution structure characterization

“…The data shown in the present article are related to our recent study of mTSPO, a mammalian translocator membrane protein, whose solution structure was compared in two surfactant environments, SDS and DPC [1] . The molecular modeling of the mTSPO-surfactant complex in the two surfactants has been performed by scattering techniques (light, X-ray and neutron scattering).…”

“…SAXS experiments were conducted for two surfactants, sodium dodecyl sulfate (SDS) and dodecyl phosphocholine (DPC), as a function of surfactant concentration above their respective CMC (critical micelle concentration), in the same buffer conditions as those used to study the membrane protein-surfactant complexes, mTSPO-SDS and mTSPO-DPC, described in [1] . Characteristic parameters of the two surfactants are presented in Table 1 .…”