Effect of amphetamine on behavior maintained by sucrose: Interaction of reinforcement schedule and food restriction

Naltrexone Reduces Ethanol‐ and/or Water‐Reinforced Responding in Rhesus Monkeys: Effect Depends Upon Ethanol Concentration

“…NTX, like amphetamine, may be acting to decrease the high rates of responding engendered by the solutions. Responding for oral fluid deliveries, in some studies, was sensitive to the rate-dependent effects of amphetamine (Carroll, 1984;Slawecki and Samson, 1996). In conditions where NTX appeared to have selective effects on a particular behavior, the animals were performing those behaviors at a high frequency.…”

Amphetamine-induced enhancement of responding for conditioned reward in rats: interactions with repeated testing

“…Psychostimulant drug addiction may be acquired through the sensitization of reward processes mediated by the mesolimbic dopamine system (Kelley 2004;Hyman et al 2006;Robinson and Berridge 2008). Thus psychostimulants potentiate instrumental responding for natural rewards depending on the reinforcement schedule (Slawecki and Samson 1996), for brain stimulation reward (Gilliss et al 2002) and for reward-predicting stimuli (Sutton and Beninger 1999). Amphetamine selectively enhances nucleus accumbens neuronal firing to a conditioned stimulus (CS) paired with sucrose in a conditioned approach task (Wan and Peoples 2008).…”