Effect of Amnioguard and Biomesh GTR Membranes with Novabone Putty in the Treatment of Periodontal Osseous Defects—A Communication

Abstract

(1) Background: Guided tissue regeneration was an effective surgical procedure in the management of intrabony defects and has undergone a number of changes in terms of materials and techniques. The aim of this study is to compare AmnioGuard and BioMesh in combination with NovaBone putty in intrabony defects. (2) Methodology: Ten patients who needed regenerative periodontal therapy were randomly allocated into two groups based on the inclusion criteria. These patients were subjected to phase I therapy followed by which Group A patients were treated with AmnioGuard + NovaBone putty whereas Group B with BioMesh + NovaBone putty. The clinical indices were obtained at baseline, 3 months and 6 months post-operatively while radiographic parameters were obtained at 6 months post-op. (3) Results & Conclusion: At six months after surgery, Group B (33% bone gain) showed a statistically significant change from Group A (16% bone gain) in both the clinical and radiographic measures (p < 0.05).

From Basic Science to Clinical Practice: A Review of Current Periodontal/Mucogingival Regenerative Biomaterials

“…NovaBone Putty (NovaBone Products, USA) is a regenerative product composed of bioactive glass with additives such as polyethylene glycol and glycerine exhibiting osteostimulatory and osteoconductive properties. [ 81 , 106 , 107 , 154 , 159 , 163 , 251 ] The bioactive glass is present in two different dimensional phases, namely 90–710 µm and 32–125 µm, and is composed only of elements that are present naturally in native bone, i.e., calcium, phosphorous, sodium, silicon, and oxygen. [ 81 , 106 , 163 ] Bioactive glass can release biologically active soluble Si 4+ and Ca 2+ ions, which stimulate bone growth and can enhance the secretion of VEGF while retarding the growth of epithelial tissue.…”

“…[ 107 , 163 , 252 ] The additives improve the handling and efficacy in clinical applications. [ 81 , 107 , 154 , 251 ]…”

“…[107,163,252] The additives improve the handling and efficacy in clinical applications. [81,107,154,251] Clinical trials involving NovaBone Putty have demonstrated its regenerative capabilities in soft and hard tissue. [81,106,107,154,159,163,251] However, one study conducted by Asmita and colleagues suggests that NovaBone Putty produces statistically similar results for the particulate form Perioglas (NovaBone Products, USA) when used for class II furcation defects.…”

“…[81,107,154,251] Clinical trials involving NovaBone Putty have demonstrated its regenerative capabilities in soft and hard tissue. [81,106,107,154,159,163,251] However, one study conducted by Asmita and colleagues suggests that NovaBone Putty produces statistically similar results for the particulate form Perioglas (NovaBone Products, USA) when used for class II furcation defects. [154] Specifically, the mean resolution in vertical defects at 6 months was 50.48 ± 16.47% for Perioglas and 43.48 ± 9.33% for NovaBone Putty.…”