2011
DOI: 10.1055/s-0031-1300449
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Effect of Amlodipine on Blood Pressure Responses in Local and Whole-body Cooling in Normotensive Men

Abstract: The objective of this study was to determine the ability of amlodipine (CAS 88150-42-9, Norvasc) to affect the cold-induced rise of blood pressure and heart rate in normotensive men. Fourteen normotensive men underwent a one-hand cold pressor test (+10 degrees C, 5 min) and a whole-body cold air exposure test (+5 degrees C, 45 min) in a crossover study with and without amlodipine at a seven-day interval. Amlodipine decreased the levels of initial systolic and diastolic blood pressure before both tests, but it … Show more

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