Effect of ambient and dietary cadmium on pavement cells, chloride cells, and Na+/K+-ATPase activity in the gills of the freshwater teleost Oreochromis mossambicus at normal and high calcium levels in the ambient water

Pratap, H.B.; Bonga, S.E. Wendelaar

doi:10.1016/0166-445x(93)90010-x

Cited by 108 publications

(42 citation statements)

References 39 publications

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“…Metal-metal interactions after single metal exposure were shown by Gill et al (1992) who reported an increased Cu concentration in the gills of eels after Cd exposure. Previous experiments with single metal exposed fish have shown effects of sublethal concentrations of Cu or Cd on the number and function of ion transporting cells in the gills (Baker, 1969;Verbost et al, 1987;Reid and McDonald, 1988;Pratap and Wendelaar Bonga, 1993;Pelgrom et al, 1995). Exposure to low Cd concentrations resulted in an unexpectedly high increase in metal concentration in the gills.…”

Section: Gillsmentioning

confidence: 91%

Interactions between copper and cadmium modify metal organ distribution in mature tilapia, Oreochromis mossambicus

Pelgrom

Lamers

Lock

et al. 1995

Environmental Pollution

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Section: Gillsmentioning

confidence: 91%

Interactions between copper and cadmium modify metal organ distribution in mature tilapia, Oreochromis mossambicus

Pelgrom

Lamers

Lock

et al. 1995

Environmental Pollution

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“…Proliferation of chloride cells is a physiological re sponse to agents affecting branchial ion uptake, such as Cd (Oronsaye and Brafield, 1984;Pratap and Wendelaar Bonga, 1993), and Cu (Baker, 1969). The increase in the number of chloride cells may be a compensatory response, playing a role in recovery from and acclimation to, heavy metals (Mallat, 1985;McDonald and Wood, 1993;Perry and Laurent, 1993).…”

Section: Chloride Cellsmentioning

confidence: 99%

Integrated physiological response of tilapia, Oreochromis mossambicus, to sublethal copper exposure

et al. 1995

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Juvenile and mature tilapia {O reochrom is m ossam bicus) were exposed to a range o f sublethal copper (Cu) concentrations for 6 days to examine the mechanisms underlying the acclimation to the toxic effects o f the metal. The study focuses on the gills, the primary target for waterborne pollutants. To obtain a comprehensive picture o f the branchial acclimation processes operating, multiple biochemical and m orphological parameters were studied. A t all concentrations tested, Cu exposure resulted in the accum ulation o f the metal in mature fish. A t 100 and 200 jug C u I-1 only, chloride cell proliferation was observed, which was accompanied by an increase in aver age cell diameter in these groups. W hole body flux measurements in juvenile fish demonstrated a decrease in N a influx in fish exposed to 200 jug I' 1 Cu, in the absence o f an effect on Ca influx. G ill N a + / K + -ATPase activity was also decreased in the crude branchial homogenates o f the mature fish exposed to the highest C u concentration only, but not in the purified branchial vesicle preparations o f these fish, which may indicate reactivation o f in vivo Cu-inhibited ATPase activity during the isolation process. Plasma pH , Na, Cl, K, glucose and ceruloplasmin concentrations were also affected in the 200 jug Cu l_l group exclusively. In accordance with the gill accum ulation data, plasma C u levels were clearly elevated in all groups exposed to the metal. The results underscore the integrated response o f the gills to Cu, which, however, does not come into play until challenged by relatively high ambient concentrations. These results indicate that, in comparison to the Cu-sensitive rainbow trout, tilapia is more Cu-tolerant. The most sensitive parameters affected by Cu are gill and plasma metal levels, followed by chloride cell num ber and diameter. Pelgrom et al. IA quatic Toxicology 32 (1995) [303][304][305][306][307][308][309][310][311][312][313][314][315][316][317][318][319][320]

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“…To assess the toxic impact of ambient levels of Cu or Cd on fish, the effects on several parameters have been studied. For example, Cu afTects the sodium balance (Reid and McDonald, 1988), growth (Lett et al, 1976), and swimming performance in rainbow trout (Waiwood and Beamish, 1978), and repro ductive success in bluntnose minnow (Horning and Nieheisel, 1979), whereas Cd affects calcium balance in rainbow trout (Verbost et al, 1987) and induces damage in gill structure of zebrafish, rainbow trout and tilapia (Karlsson-Norrgren et al, 1985;Pratap and Wendelaar Bonga, 1993). It is evident from these studies that increased tissue concentrations of heavy metals induce significant stress in the animals.…”

Section: Introductionmentioning

confidence: 98%

Interactions between copper and cadmium during single and combined exposure in juvenile tilapia Oreochromis mossambicus: Influence of feeding condition on whole body metal accumulation and the effect of the metals on tissue water and ion content

et al. 1994

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Aquatic Toxicology 30 (1994) 117-135 ; Interactions between copper and cadmium during single and combined exposure in juvenile tilapia O r e o c h r o m i s m o s s a m b i c u s :Influence of feeding condition on whole body metal accumulation and the effect of the metals on tissue water and ion content AbstractJuvenile tilapia (Oreochromis mossamhicus) were exposed for 96 h to ranges of sublethal concentrations of Cu or Cd, under both fed and non-fed conditions. Exposure to one metal (Cu or Cd) not only resulted in an increased whole body content of the metal exposed to, but also influenced the concentration of the other metal present in the fish. Furthermore, the total amount of Cu and Cd accumulated during exposure to heavy metals was influenced by the nutritional state of the fish. Besides exposure to either Cu or Cd, fish were also exposed to mixtures of Cu and Cd. Results indicated that accumulation during Cu/Cd co-exposure cannot be predicted by simple addition of the effects of single metal exposures. Obviously, complex interaction mechanisms are involved, as was concluded e.g. from the significantly decreased whole body Cd-content of Cu/Cd-co-exposed fish compared to the Cd-content of Cd-exposed fish. This phenomenon was observed in both fed and non-fed fish. Because ionic homeostasis is known to be affected by heavy metals, in this study also whole body water, calcium and sodium content in Cu and/or Cd-exposed fish were determined. The results indicate that also with respect to these parameters the two metals interact. The effects on water and ion appear to be dissociated. The data reveal previously unrecognized effects of interaction of the metals on whole body metal content, water and ion regulation.

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Effect of ambient and dietary cadmium on pavement cells, chloride cells, and Na+/K+-ATPase activity in the gills of the freshwater teleost Oreochromis mossambicus at normal and high calcium levels in the ambient water

Cited by 108 publications

References 39 publications

Interactions between copper and cadmium modify metal organ distribution in mature tilapia, Oreochromis mossambicus

Interactions between copper and cadmium modify metal organ distribution in mature tilapia, Oreochromis mossambicus

Integrated physiological response of tilapia, Oreochromis mossambicus, to sublethal copper exposure

Interactions between copper and cadmium during single and combined exposure in juvenile tilapia Oreochromis mossambicus: Influence of feeding condition on whole body metal accumulation and the effect of the metals on tissue water and ion content

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