Abstract:Circadian rhythm of 18-hydroxycorticosterone (18-OHB), a possible immediate precursor of aldosterone (Fraser and Lantos 1978), has been demonstrated in man (Wilson, Mason and Fraser 1976; Sowers, Martin and Beck 1983) and rats (Imaizumi, Yamamoto, Kamei, Yoshida, Miyauchi, Kigoshi, Hosojima, Uchida and Morimoto 1987). This circadian rhythm of plasma 18-OHB resembles that of plasma aldosterone or glucocorticoid under regular conditions, whereas their circadian peaks occur in the morning in the diurnally-activ… Show more
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