Effect of aloe vera mouthwash on dental plaque and gingivitis indices in children: A randomized controlled clinical trial

Aloe vera mouthwashes can be a natural alternative to chemically formulated ones – A randomized-controlled trial

“…In our study, mouthwash containing chlorhexidine was used as a positive control as in several previous studies for comparison with other mouthwash formulations or products. 25 , 26 , 27 , 28 CHX is considered the gold standard owing to its superior antiplaque and antimicrobial efficacy. 29 , 30 It is helpful to include the most efficacious and widely used products in comparative studies for greater validity.…”

Comparative evaluation of various herbal extracts on biofilms of Streptococcus mutans and Scardovia wiggsiae: An in vitro study

“…22 Due to the increasing prevalence of resistant organisms and adverse effects of current treatment approaches in children, interest in natural compounds, particularly herbal extracts, has been rapidly increasing. 6,21 Efforts have been made to use natural products instead of synthetic antimicrobial compounds in the development of anti-caries agents. 7 Despite previous studies demonstrating the association of S. wiggsiae with early carious lesions, no exclusive studies have been found in the literature on the use of S. wiggsiae in two-species biofilms formed on human teeth.…”

“…21 It has, however, many adverse effects such as discoloration of the teeth, restorative materials, and the tongue; altered sense of taste; increased risk of mucosal erosion; and increase in supragingival calculus formation. 6 In addition, due to its broad-spectrum bactericidal property, CHX has been reported to eradicate commensal bacteria, eventually leading to imbalanced oral microbiota. 22 Due to the increasing prevalence of resistant organisms and adverse effects of current treatment approaches in children, interest in natural compounds, particularly herbal extracts, has been rapidly increasing.…”

“…5 Chlorhexidine (CHX) is a broad-spectrum antibacterial agent. 6 Yet, traditional chemotherapeutic agents and adverse effects frequently associated with commonly used synthetic oral biocides, such as CHX (eg, staining oral tissues and burning the tongue), 6 and concern about microbial resistance to these agents have raised the need for safer and more effective alternative agents. 7 In recent years, chemicals that are widely used to prevent dental caries have been identified to pose high risk, particularly in young children and disabled individuals who are not able to expectorate; therefore, plants with antimicrobial ingredients have attracted attention.…”

Herbal mouthwashes for oral health care-A paradigm shift

“…The active compounds include aloesin, aloin, aloeride, naftoquinones, methylchromones, flavonoids, saponin, sterols, etc. 10 It is antibacterial, anti-inflammatory, antiulcer, and antioxidant in action. 11 Aloe vera mouthwashes have become increasingly popular because of its safety, easy availability, and its effectiveness against plaque causing bacteria.…”