Topography-mediated antibacterial
surfaces that inactivate bacteria
by physical contact have gained attention in recent years. Contrary
to conventional antibacterial coatings, topography-mediated antibacterial
surfaces do not suffer from coating instability and possible toxicity
problems. In this study, a one-step hard anodization process has been
deployed to fabricate a topography-mediated antibacterial aluminum
surface. By optimizing anodization parameters, such as the concentration
of the electrolyte, current density, and anodization time, desirable
features of micronanoscale morphology were achieved. The optimum conditions
of anodized aluminum that provided pores of a diameter of 151 ±
37 nm effectively killed 100% of E. coli bacteria.