Effect of aerobic training on nerve conduction in men with type 2 diabetes and peripheral neuropathy: A randomized controlled trial

Resistance training improves nerve conduction and arterial stiffness in older adults with diabetic distal symmetrical polyneuropathy: A randomized controlled trial

“…Nerve conduction velocity and nerve APA improved following 12-week resistance exercise regimen in older adults with DSPN. This finding is partly in accordance with some previous studies that reported enhanced NCV of sensory and motor nerves following aerobic exercise training [26,27]. The evidence showed that the neural system responds positively to physical activity through morphological and functional adaptations to the training stimulus [6,[28][29][30].…”

“…The calcualtion was based on a medium effect size (= 0.06) for interaction between time and group, α = 0.05, and power of 80% [26]. Based on a previous study, the correlation between repeated measures was assumed to be 0.6 for nerve conduction velocity [27]. According to these assumptions a sample size of 28 was required.…”

Aerobic exercise can modulate the underlying mechanisms involved in the development of diabetic complications

“…AE may be beneficial for the protection of neuronal networks against diabetes-induced pathophysiologic mechanisms (Kluding et al, 2012(Kluding et al, , 2015. Evidence from both experimental animals and humans suggests that AE can improve neuronal function by inhibition of neuronal toxicity and neuropathies (Gholami, Nikookheslat, Salekzamani, Boule, & Jafari, 2018;Kluding et al, 2015). Balducci et al (2006) suggested that AE slows DP progression by improving nerve conduction velocity (NCV), nerve distal latency, vibration perception threshold, and nerve action potential amplitude in the lower limbs of diabetic patients.…”

Effects of Physical Exercises on Peripheral Neuropathy Sensation in Patients with Type 2 Diabetes

“…The search results only found 11 articles discussing physical exercise in relation to sensation of peripheral neuropathy (Table 1). From these 11 articles, analysis was carried out and it can be concluded that there are two effects that physical exercise has on diabetic peripheral neuropathy, namely a direct positive effect on neuropathy (Dixit et al, 2019;Kanchanasamut & Pensri, 2017;Matos et al, 2018;Nadi et al, 2017;Navarro-peternella & Teston, 2019;Zilliox & Russell, 2019;Johnson & Takemoto, 2019;Stubbs Jr et al, 2019;Gholami et al, 2020) and indirect effects on neuropathic sensation (Gholami et al, 2018;Seyedizadeh et al, 2020).…”

“…The progressive nature of peripheral neuropathy has slightly changed (Seyedizadeh et al, 2020). With the same research method, research (Gholami et al, 2018) on 24 DM peripheral neuropathies divided into 12 exercise groups, 12 control groups, where the experimental group first conducted 3 socialization sessions a week before the main intervention, then the respondents underwent aerobic exercise program for three months (walking, jogging or running on a treadmill, 3 sessions a week, 50-70% HRR, 20-45 minutes). The results showed that the sural sensory nerve conduction velocity (NCV) in the exercise group significantly increased (from 35.2 ± 4.3 m / s to 37.3 ± 6.2 m / s) compared to the control group (P = 0.007).…”