Effect of adult COVID-19 surge on the provision of kidney replacement therapy in children

Anticoagulation strategies in continuous kidney replacement therapy — does one size fit all?

“…In addition to combination of anticoagulants to prevent frequent filter-clotting, higher doses compared to traditional doses could be used to achieve better anticoagulation in this hypercoagulable state (higher ACT/APTT in UFH or lower ionised calcium within the circuit in RCA). As long as we understand the underlying disease physiology and the side-effect profile and mitigation measures, bespoke anticoagulation strategies can be safely applied [ 14 ].…”