Effect of Adrenaline, Fentanyl and Warming of Injectate on Shivering following Extradural Analgesia in Labour

Shehabi, Yahya; Gatt, Stephen; Buckman, Thomas E.; Isert, P.

doi:10.1177/0310057x9001800106

Cited by 42 publications

(8 citation statements)

References 18 publications

(3 reference statements)

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“…This was to limit the large fall in temperature ofthe lignocaine solution with time. 4 The onset of sensory blockade was defined as loss of perianal sensation to pinprick with a 27 gauge short-bevel disposable needle. Assessments of sensory blockade were made after the caudal injection of the local anaesthetic solution at oneminute intervals until loss of perianal sensation to pinprick.…”

Section: Methodsmentioning

confidence: 99%

Use of Warm Local Anaesthetic Solution for Caudal Blocks

Lim

Chong

Singh

et al. 1992

Anaesth Intensive Care

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A double-blind study was undertaken to investigate the effect of prewarmed local anaesthetic solution on the latency of onset of caudal blocks. Forty-four (ASA I-II) patients were allocated into two equal groups. In Group A, the local anaesthetic solutions were injected at room temperature (25°C), while in Group B, they were injected at 3rc. All the caudal blocks were performed using 20 ml of lignocaine 1.5% with adrenaline 1:200,000. The speed of onset of perianal analgesia was found to be significantly faster (39%) with the prewarmed local anaesthetic solution (P < 0.05). No adverse effects were observed.

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Section: Methodsmentioning

confidence: 99%

Use of Warm Local Anaesthetic Solution for Caudal Blocks

Lim

Chong

Singh

et al. 1992

Anaesth Intensive Care

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“…It has been reported that PAS could be prevented by warming skin-surface [6] and warming the administered fluid [7,8], but it is not a perfect way. Many drugs have been shown to be effective on prevention of PAS, such as opioids, α2-agonist, anticholinergic, CNS stimulant, corticosteroid [9], however, few of them were recommended for the prevention of PAS due to various side-effects.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of ondansetron in preventing postanesthesia shivering: a meta-analysis of randomized controlled trials

Tie

et al. 2014

BMC Anesthesiol

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BackgroundShivering is a very common complication in the postanesthesia period. Increasing studies have reported ondansetron may be effective in prevention of postanesthesia shivering (PAS). However, the results remained controversial; hence we conducted a meta-analysis of randomized controlled trials to evaluate the efficacy and safety of ondansetron on the prevention of postanesthesia shivering.MethodsPubMed and Embase databases were searched to identify the eligible randomized controlled trials assessing the effect of ondansetron on the prevention of PAS. Results were expressed as risk ratios (RRs) with accompanying 95% confidence intervals (CIs). The meta-analysis was performed with fixed-effect model or random-effect model according to the heterogeneity.ResultsSix trials including 533 subjects were included. Compared with placebo, ondansetron was associated with a significant reduction of PAS (RR 0.43, 95% CI, 0.27-0.70), without an increased risk of bradycardia (RR 0.37, 95% CI, 0.12-1.15). Compared with meperidine, no difference was observed in the incidence of PAS (RR 0.68, 95% CI, 0.39-1.19) and bradycardia (RR 2.0, 95% CI, 0.38-10.64).ConclusionsOndansetron has a preventive effect on PAS without a paralleled side effect of bradycardia.

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“…Lim et al 21 did not find any difference in shivering between patients receiving epidural 1.5% lidocaine with epinephrine 1:200 000 (20 mL) at body or room temperature. In contrast, Shehabi et al 22 found that patients receiving warmed compared to room temperature epidural bupivacaine had a lower incidence of shivering. Furthermore, Walmsley et al 23 demonstrated that the administration of warmed epidural bupivacaine resulted in the cessation of active shivering.…”

Section: Discussionmentioning

confidence: 90%