Effect of acute heat stress on rat adrenal medulla — a morphological and ultrastructural study

Abstract

Isolated rat adrenal medulla was analyzed by light and electron microscope after an acute (60 min) exposure to high ambient temperature (38°C). Under these conditions there was a significant rise in plasma adrenaline and noradrenaline. Stereological investigation by light microscopy showed a significant decrease in volume density of cells and an increase in the interstitium. At the ultrastructural level, the profile area of cells, nuclei and cytoplasm of adrenaline cells were significantly decreased. After the heat stress numbers of resting granules in adre naline and noradrenaline cells were significantly reduced, while the numbers of altered granules and empty containers in both types of adrenomedullar cells were significantly increased.

Chronic dehydration affects hydroelectrolytic equilibrium and adrenal gland morphology in wistar rat: comparison with <i>Gerbillus tarabuli</i>

“…Such a degranulation of chromaffin cells has been also observed in rat after various stressors [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22]. Also, signs of cell degeneration were evidenced in chromaffin cells displayed by hypertrophy of cells with loss of cell borders, vacuolation of cytoplasm, and pyknotic nuclei.…”

Protective Effect of Capsaicin Against Brain Oxidative Stress Induced by Heat Stress in Apri Rabbits

“…Nevertheless, the noradrenaline content of the brain was significantly increased in 30 and 50 mg/kg body weight groups compared with other groups during summer season. Heat exposure led to increase concentrations of plasma and changes in the cells of adrenal gland medulla in the rats (Petrovic-Kosanovic et al, 2012). Also, Yuan et al (1989) found that heat exposure for 15 min at 45°C reduced the brain content of noradrenaline (NA) in mice.…”