Effect of active airway warming with a heated-humidified breathing circuit on core body temperature in patients under general anesthesia: a systematic review and meta-analysis with trial sequential analysis

Lee, Je Jin; Choi, Geun Joo; Lee, Wonjun; Choi, Sang Bong; Kang, Hyun

doi:10.4097/kja.22200

Cited by 5 publications

(4 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Owing to the growing recognition of the importance of evidence-based medicine, the number of meta-analyses and network meta-analyses published that quantitatively synthesize the results of RCTs has increased [ 5 , 6 ]. In meta-analyses or network meta-analyses, the choice of group-defining strategies among ITT, AT, and PP can result in significantly different outcomes [ 7 ].…”

Section: Bias Caused By Non-compliance or Non-adherence To Study Prot...mentioning

confidence: 99%

Intention-to-treat versus as-treated versus per-protocol approaches to analysis

Ahn,

Kang

2023

Korean J Anesthesiol

Self Cite

View full text Add to dashboard Cite

Randomized controlled trials (RCTs) are considered the most rigorous study design for testing hypotheses and the gold standard for evaluating intervention effectiveness. However, RCTs are often conducted under the assumption of ideal conditions that may differ from real-world scenarios in which various issues, such as loss to follow-up, mistakes in participant enrollment or intervention, and low subject compliance or adherence, may occur. There are various group-defining strategies for analyzing RCT data, including the intention-to-treat (ITT), as-treated, and per-protocol (PP) approaches. The ITT principle involves analyzing all participants according to their initial group assignments, regardless of study completion and compliance or adherence to treatment protocols. This approach aims to replicate real-world clinical settings in which several anticipated or unexpected conditions may occur with regard to the study protocol. For the PP approach, only participants who meet the inclusion criteria, complete the interventions according to the study protocols, and have primary outcome data available are included. This approach aims to confirm treatment effects under optimal conditions. In general, the ITT principle is preferred for superiority and inequality trials, whereas the PP approach is preferred for equivalence and non-inferiority trials. However, both analytical approaches should be conducted and their results compared to determine whether significant differences exist. Overall, using both the ITT and PP approaches can provide a more complete picture of the treatment effects and ensure the reliability of the trial results.

show abstract

Section: Bias Caused By Non-compliance or Non-adherence To Study Prot...mentioning

confidence: 99%

Intention-to-treat versus as-treated versus per-protocol approaches to analysis

Ahn,

Kang

2023

Korean J Anesthesiol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Proper humidification is crucial to prevent drying and damage to the respiratory tract, particularly during prolonged mechanical ventilation. Humidifiers provide controlled humidification to maintain optimal lung function and reduce complications associated with dry airway passages [41].…”

Section: Mechanical Ventilation Systemmentioning

confidence: 99%

Assessing the impact of battery charging and discharging times on the availability of mechanical ventilation service

Monte,

Pessoa,

Silva

et al. 2023

J Reliable Intell Environ

View full text Add to dashboard Cite

This paper evaluates the impact of battery charging and discharging times on the availability of mechanical respirators in the intensive care unit (ICU). The availability of these life-saving devices is crucial for ensuring optimal patient care in critical situations. This study aims to assess how the duration of battery charging and discharging cycles affects the availability of mechanical respirators and explore potential strategies to optimize their maintainability. We analyze the system's behavior in eight scenarios that consider changes to optimize repair times, battery charge and discharge times, and power system redundancy. The results showed 98% improvements in availability and reduced system downtime. The outcomes of this research contribute to understanding the critical factors impacting the availability of mechanical respirators in the ICU. By addressing the issues related to battery charging and discharging times and maintaining these devices, healthcare facilities can enhance the availability and reliability of respiratory support systems. Ultimately, this study aims to improve patient outcomes and promote efficient resource utilization in the ICU setting.

show abstract

“…[1,2] Anesthesia-induced inhibition of thermoregulatory control together with exposure to cool environments results in major thermal abnormalities. [3][4][5][6][7] However, in some cases, the body temperature may increase. The increase in core body temperature occurs through a multiphasic response of the central body temperature to a central thermoregulatory mechanism localized in the preoptic area of the hypothalamus.…”

Section: Introductionmentioning

confidence: 99%

Increase in body temperature in pediatric patients after costal cartilage harvest in microtia reconstruction: A retrospective observational study

et al. 2022

View full text Add to dashboard Cite

Background: Previous evidence has clearly shown that maintaining normothermia in children undergoing surgery is difficult and is associated with adverse outcomes. Therefore, this study aimed to retrospectively analyze the changes in body temperature over time in 2 different types of microtia reconstruction surgeries, namely, embedding, and elevation surgeries. Methods: We performed a retrospective chart review of patients who underwent microtia reconstruction (embedding and elevation) between July 2012 and February 2015 (n = 38). The changes in body temperature between the 2 types of surgeries were compared. Results: During microtia reconstruction, the body temperature in the embedding surgery group was significantly higher than that in the elevation surgery group from 1 hour after the start of surgery to 1 day after the surgery ( P < .001). Time, group, and time-group interaction were associated with an increase in body temperature ( P < .001) but not the warming method. Conclusion: We found an increase in body temperature in patients with microtia who underwent embedding surgery (autologous costal cartilage harvest surgery), and this was related to the type of surgery and not to the warming method. Therefore, further research is warranted to determine the cause of the increase in body temperature during this surgery.

show abstract

Effect of active airway warming with a heated-humidified breathing circuit on core body temperature in patients under general anesthesia: a systematic review and meta-analysis with trial sequential analysis

Abstract: This article has been accepted for publication and has undergone full peer review but has not been through the copyediting, typesetting, pagination, and proofreading processes, which may lead to differences between this version and the version of record.

Cited by 5 publications

References 47 publications

Intention-to-treat versus as-treated versus per-protocol approaches to analysis

Intention-to-treat versus as-treated versus per-protocol approaches to analysis

Assessing the impact of battery charging and discharging times on the availability of mechanical ventilation service

Increase in body temperature in pediatric patients after costal cartilage harvest in microtia reconstruction: A retrospective observational study

Contact Info

Product

Resources

About