Effect of Acetaminophen (APAP) on Physiological Indicators in Lactuca sativa

Kudrna, Jiří; Hnilička, František; Kubeš, Jan; Vachová, Pavla; Hniličková, Helena; Kuklová, Margita

doi:10.3390/life10110303

Cited by 12 publications

(9 citation statements)

References 65 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…NSAID-induced alterations in the photosynthetic machinery as assimilation rates and stomatal conductance to water vapor decrease for all species. A similar pattern was determined in Lactuca sativa plants treated with 0.76 g L −1 paracetamol [30] and in bean plants treated with 0.30 g L −1 paracetamol [32]. Interestingly, there were differences in the assimilation rates for plants treated with different medicines, but no pattern could be observed.…”

Section: Discussionsupporting

confidence: 76%

“…The paracetamol treatment affected the chlorophyll accumulation with 1.4-22.4 mg L −1 after a 21-day exposure [29]. Separate research showed that lettuce plants (Lactuca sativa L.) treated with high quantities of paracetamol had a considerable drop in photosynthesis and chlorophyll fluorescence, suggesting a possible influence on photosystem II quantum efficiency [30]. It was discovered that indometacin had a dose-dependent effect on algal growth, macromolecular synthesis, and metabolism.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

et al. 2022

View full text Add to dashboard Cite

Nonsteroidal anti-inflammatory medications (NSAIDs) are commonly used painkillers, anti-inflammatory agents, and fever reducers. They arrive in the environment from municipal wastewater and/or agriculture waste, affecting growing plants. In our study, the impact of NSAIDs, namely, diclofenac, indomethacin, naproxen, and paracetamol, on four plant species from the Fabaceae family (Cicer arietinum, Pisum sativum, Lens culinaris, and Vicia faba) was tested. The assimilation rate and stomatal conductance decreased for all plants treated with NSAIDs. Chlorophyll and carotenoid contents in the leaves of plants under stress declined by more than 15% compared with the control plants, while the flavonoids and total phenols decreased to a lesser extent. In contrast, the plants treated with NSAIDs emit terpenes and green leaf were volatile, at a level of some nmol m−2 s−1, which could influence the atmospheric reaction and ozone formation.

show abstract

Section: Discussionsupporting

confidence: 76%

Section: Introductionmentioning

confidence: 99%

Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The minimum chlorophyll Chl a fluorescence (F 0 ) and the maximum Chl a fluorescence (F m ) were measured with a portable fluorometer OSI 1 FL (Opti-Sciences, ADC, BioScientific, Ltd., UK), as previously described [ 88 ]. Briefly, F 0 and F m were measured with 0.8 s excitation pulse (660 nm) and saturation intensity of 15,000 µmol/m 2 s after 20 min of dark adaptation in the leaves.…”

Section: Methodsmentioning

confidence: 99%

Arsenic Toxicity-Induced Physiological and Metabolic Changes in the Shoots of Pteris cretica and Spinacia oleracea

Zemanová

Pavlı́ková

Hnilička

et al. 2021

Plants

Self Cite

View full text Add to dashboard Cite

Arsenic is a ubiquitous toxic element that can be accumulated into plant parts. The present study investigated the response of Pteris cretica and Spinacia oleracea to As treatment through the analysis of selected physiological and metabolic parameters. Plants were grown in pots in As(V) spiked soil (20 and 100 mg/kg). Plants’ physiological condition was estimated through the determination of elements, gas-exchange parameters, chlorophyll fluorescence, water potential, photosynthetic pigments, and free amino acid content. The results confirmed differing As accumulation in plants, as well as in shoots and roots, which indicated that P. cretica is an As-hyperaccumulator and that S. oleracea is an As-root excluder. Variations in physiological and metabolic parameters were observed among As treatments. Overall, the results revealed a significant effect of 100 mg/kg As treatment on the analysed parameters. In both plants, this treatment affected growth, N, Mg, S, Mn, and Zn content, as well as net photosynthetic rate, chlorophyll fluorescence, and total free amino acid content. In conclusion, the results reflect the similarity between P. cretica and S. oleracea in some aspects of plants’ response to As treatment, while physiological and metabolic parameter changes related to As treatments indicate the higher sensitivity of S. oleracea.

show abstract

“…In addition to their persistence and various acute toxicities, some authors have reported the decline of the vulture population in Switzerland, India, Pakistan, Bangladesh, and Nepal as a result of poisoning with NSAIDS [ 21 , 22 , 23 ]. High toxicity to plants and microorganisms has also been reported [ 24 , 25 , 26 ].…”

Section: Introductionmentioning

confidence: 99%

Predicting the Adsorption of Amoxicillin and Ibuprofen on Chitosan and Graphene Oxide Materials: A Density Functional Theory Study

et al. 2021

View full text Add to dashboard Cite

The occurrence, persistence, and accumulation of antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) represent a new environmental problem due to their harmful effects on human and aquatic life. A suitable absorbent for a particular type of pollutant does not necessarily absorb other types of compounds, so knowing the compatibility between a particular pollutant and a potential absorbent before experimentation seems to be fundamental. In this work, the molecular interactions between some pharmaceuticals (amoxicillin, ibuprofen, and tetracycline derivatives) with two potential absorbers, chitosan and graphene oxide models (pyrene, GO-1, and coronene, GO-2), were studied using the ωB97X-D/6-311G(2d,p) level of theory. The energetic interaction order found was amoxicillin/chitosan > amoxicillin/GO-1 > amoxicillin/GO-2 > ibuprofen/chitosan > ibuprofen/GO-2 > ibuprofen/GO-1, the negative sign for the interaction energy in all complex formations confirms good compatibility, while the size of Eint between 24–34 kcal/mol indicates physisorption processes. moreover, the free energies of complex formation were negative, confirming the spontaneity of the processes. The larger interaction of amoxicillin GOs, compared to ibuprofen GOs, is consistent with previously reported experimental results, demonstrating the exceptional predictability of these methods. The second-order perturbation theory analysis shows that the amoxicillin complexes are mainly driven by hydrogen bonds, while van der Waals interactions with chitosan and hydrophobic interactions with graphene oxides are modelled for the ibuprofen complexes. Energy decomposition analysis (EDA) shows that electrostatic energy is a major contributor to the stabilization energy in all cases. The results obtained in this work promote the use of graphene oxides and chitosan as potential adsorbents for the removal of these emerging pollutants from water.

show abstract

Effect of Acetaminophen (APAP) on Physiological Indicators in Lactuca sativa

Cited by 12 publications

References 65 publications

Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

Influence of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) on Photosynthetic Parameters and Secondary Metabolites of Plants from Fabaceae Family

Arsenic Toxicity-Induced Physiological and Metabolic Changes in the Shoots of Pteris cretica and Spinacia oleracea

Predicting the Adsorption of Amoxicillin and Ibuprofen on Chitosan and Graphene Oxide Materials: A Density Functional Theory Study

Contact Info

Product

Resources

About