Effect of a1-Adrenoceptor Blockade on Maximal V02 and Endurance Capacity in Well- rained Athletic Hypertensive Men

Tomten, Sissel E.; Kjeldsen, Sverre E.; Nilsson, Svein; Westheim, Arne

doi:10.1093/ajh/7.7.603

Cited by 9 publications

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“…Alpha blockers may be prescribed as a replacement or additional therapy. They reduce systemic vascular resistance without increasing heart rate or cardiac output and have been shown to lower systolic blood pressure immediately after running [17,68]. However, a crossover study has shown that alpha blockers significantly decrease VO 2 max and physical endurance performance in athletic men with mild hypertension, leading to the conclusion that alpha blockers should be used primarily as second-line therapy [68].…”

Section: Treatment Of Hypertensive Athletesmentioning

confidence: 99%

Athletes and Hypertension

et al. 2021

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Purpose of Review We reviewed most current medical literature in order to describe the epidemiology, clinical manifestation, outcome, and management of hypertension in athletes. Recent Findings An estimated quarter of the world’s population is suffering from hypertension and this prevalence is also reflected in athletes and in individuals involved in leisure time sport activities. Several studies found an inverse relationship between physical activity and blood pressure. Therefore, physical exercise is recommended to prevent, manage, and treat hypertension. On the other hand, the prevalence of hypertension may vary by sport and in some cases may even be higher in athletes competing in certain disciplines than in the general population. Hypertension is the most common medical condition in athletes and may raise concerns about its management and the individual’s eligibility for competitive sports. A thorough clinical evaluation should be performed to correctly diagnose or rule out hypertension in athletes, describe the individual’s risk profile, rule out secondary causes, and detect possible hypertension-mediated organ damage caused by hypertension at an early stage. Based on most recent clinical research and international consensus documents, we propose a diagnostic algorithm as well the non-pharmacological and pharmacological management of hypertension in athletes. Summary Although elevated blood pressure levels are less common in the active population, athletes are not protected from hypertension. A thorough diagnostic approach may help to identify individual at risk for adverse cardiovascular events and to address the optimal treatment as well as sport recommendations.

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Section: Treatment Of Hypertensive Athletesmentioning

confidence: 99%

Athletes and Hypertension

et al. 2021

View full text Add to dashboard Cite

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“…I pushed myself through another grueling week of running, then increased the terazosin to 15 mg. Two days and a dozen miserable miles later, I finally peeked into PubMed and found a 1994 cross-over study of doxazosin in hypertensive athletes that convincingly demonstrated impaired performance in 5000 meter runs. 1 A 1995 study found that doxazosin significantly increased 2-mile running time in non-elite athletes. 2 Within 2 days of stopping terazosin, I was again running well.…”

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confidence: 99%