Effect of a stannous fluoride-containing dentifrice on caries reduction in children II. Caries experience after one year

Muhler, Joseph C.; Radike, Arthur W.; Nebergall, William H.; Day, Harry G.

doi:10.14219/jada.archive.1955.0028

Cited by 37 publications

(11 citation statements)

References 8 publications

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“…Laboratory experiments showed that stannous fluoride could be suitable, and the results of a one year trial of a toothpaste containing stannous fluoride with a calcium pyrophosphate abrasive were published in 1955, showing a substantial caries-preventive effect (13). This was marketed with the name 'Crest' in the USA in the same year.…”

Section: Toothpastesmentioning

confidence: 99%

Fluoride toothpastes and fluoride mouthrinses

Rugg-Gunn

Bánóczy

2013

AMA

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Section: Toothpastesmentioning

confidence: 99%

Fluoride toothpastes and fluoride mouthrinses

Rugg-Gunn

Bánóczy

2013

AMA

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“…These results are similar to the figures on caries increment reported in a study of Indiana school children. 22 The distribution of children having different magnitudes of total salivary lactobacilli counts was not different in the 2 dentifrice groups at the beginning or at the end of the test year. It appears that there was no difference in the effects of the dentifrices on total numbers of salivary lactobacilli.…”

Section: Resultsmentioning

confidence: 82%

Studies on Salivary Lactobacilli and Dental Caries in Children During a Dentifrice Test Program

1957

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TlIHE primary purpose of this study was to test the effect of a dentifrice containing a dichlorophenyl methane compound on dental caries increment in a group of children. Several members of a series of halogenated diphenols had been shown to be highly bacteriostatic against mouth organisms at very low concentrations. Usage tests with a number of dentifrice formulations indicated that bis-(2-hydroxy-4, 5-dichlorophenyl) methane, which demonstrated considerable antibacterial activity, could be used at a level of 0.2 per cent without causing any irritation of the oral tissues. Other compounds thus tested were eliminated on the basis of irritativeness. The second purpose was to study salivary lactobacilli in the children, and the effect of the dentifrice on these organisms.The question of the association of oral lactobacilli with dental caries has been the subject of considerable study and some controversy. Bunting and Palmerleel found that the presence of oral lactobacilli could be correlated with dental caries activity. Later reports confirmed this observation, all considering lactobacilli, qualitatively.2-6 In much of this early work, assay was made of tooth scrapings rather than of saliva.Hadley8 developed a generally satisfactory method for quantitative estimation of numbers of lactobacilli in saliva. She reported that zero counts of lactobacilli were obtained in the majority of saliva samples from caries-free persons, while counts of over 20,000 lactobacilli per cubic centimeter were obtained from the majority of saliva samples from caries-susceptible persons. Other investigators,8-10 using the Hadley technic, attempted to extend the salivary lactobacilli-caries relationship into quantitative aspects, but without critical evaluation of the significance of different levels of lactobacilli counts per cubic centimeter of saliva.Snyder", 12 evaluated the relation of salivary lactobacilli to caries in a more strictly quantitative manner. He confirmed the association, but stated that prediction of future dental caries on the basis of existent salivary lactobacilli counts was possible only with groups, not with single individuals. Due to sporadic occurrence of lactobacilli, he proposed that evaluation of the caries activity of an individual should be based on several spaced saliva examination.12 Jay"3 stated, "Counts under 2,000 are, as a rule, unimportant. Counts from 2,000 to 10,000 are usually indicative of moderate caries activity, while counts over 10,000 generally require strict dietary treatment."

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“…The main oral health benefit of brushing with fluoride toothpastes is the delivery of fluoride to the mouth and concomitant caries reductions. These reductions have been demonstrated over several decades by toothpastes with numerous combinations of fluoride salts and abrasive systems [61][62][63][64][65][66][67][68][69][70][71][72][73][74][75][76] .…”

Section: Fluoridementioning

confidence: 99%

In vitro assessment of a toothpaste range specifically designed for children

Stovell

Newton

Lynch

2013

International Dental Journal

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A number of factors should be taken into account when designing toothpaste formulations for use by children at the different stages of their development. While adult toothpaste formulations may provide caries prevention benefits for children at risk of caries, these formulations may also contain higher levels of abrasive in order to address the staining needs of the adult population owing to smoking and the consumption of dietary chromogens such as coffee and tea, which are not normally found in the diet of children. While toothpastes formulated for adults are also likely to contain higher concentrations of surfactant and flavour, many children prefer toothpastes with mild flavours and modest foaming characteristics. An ideal children's toothpaste formulation should therefore aim to maximise fluoride availability, with appropriate abrasivity, while still delivering effective cleaning, as well as levels and types of flavour and surfactant to provide an acceptable brushing experience. Selection of toothpaste flavour types for children of different ages should ideally be based directly upon preference data from children. Flavours perceived as pleasant during brushing studies have been linked to increased brushing time, which, in turn, can increase the delivery and efficacy of fluoride from toothpastes. Therefore, manufacturers select tested, child-friendly flavours to maximise compliance, providing a more pleasurable brushing experience and oral health benefits.

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Effect of a stannous fluoride-containing dentifrice on caries reduction in children II. Caries experience after one year

Cited by 37 publications

References 8 publications

Fluoride toothpastes and fluoride mouthrinses

Fluoride toothpastes and fluoride mouthrinses

Studies on Salivary Lactobacilli and Dental Caries in Children During a Dentifrice Test Program

In vitro assessment of a toothpaste range specifically designed for children

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