Effect of a pre-filter on the sensitivity of a highresolution quadrupole mass spectrometer

Hiroki, Seiji; Sakata, Kenichi; Sugiyama, Naoki; Muramoto, Shin; Abe, Tetsuya; Murakami, Yoshio

doi:10.1016/0042-207x(94)00149-9

Cited by 8 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4 and 9). This concept can easily be extended to more complex features such as Einzel lenses as well as prefilters and postfilters to improve performance [74], [75]. A simple change in the mask layout can be used to produce these additional features.…”

Section: Discussionmentioning

confidence: 99%

Chip-Scale Quadrupole Mass Filters for Portable Mass Spectrometry

Cheung

Velásquez–García

Akinwande

2010

J. Microelectromech. Syst.

View full text Add to dashboard Cite

We report the design, fabrication, and characterization of a new class of chip-scale quadrupole mass filter (QMF). The devices are completely batch fabricated using a wafer-scale process that integrates the quadrupole electrodes, ion optics, and housing into a single monolithic block. This process eliminates the electrode-to-housing misalignments inherent in other QMFs and enables the implementation of complex device architectures. To achieve the reported integration, 1 mm × 1 mm square electrodes of heavily doped silicon were utilized, resulting in quadrupoles with an effective aperture radius of 0.707 mm and a length of 30 mm. Mass filtering was demonstrated with this unconventional device showing a mass range of 650 amu and a resolution of ∼30 at a drive frequency of 1.8 MHz. When operated in the second stability region at 2.0 MHz and a mass range of 50 amu, a peak width of 0.3 amu was achieved at mass 28, showing a resolution of ∼90. This paper introduces operation in the second stability region as a reliable method for turning QMFs with less than ideal electrode geometries into high-performance devices. [2009-0325] Index Terms-Chip-scale quadrupole, mass filter, second stability region, square electrodes. I. INTRODUCTION M ASS spectrometers are powerful analytical instruments that have a wide range of applications spanning national security, environmental monitoring, space exploration, industrial processing, healthcare, and many others. In recent years, there has been a growing desire to take these useful tools into space and into the field to perform analyses in harsh environments. To achieve this migration, mass spectrometers need to be small, light, mechanically and thermally robust, and low powered. Miniaturization addresses most of these requirements by achieving portability from the reduction of size and weight. Additionally, the smaller devices will enable operation at higher pressures, relaxing the need for large, heavy, and power-hungry vacuum pumps [1]-[4]. The four major components of a mass spectrometer are the ionizer, the mass analyzer, the detector, and the vacuum pump.

show abstract

Section: Discussionmentioning

confidence: 99%

Chip-Scale Quadrupole Mass Filters for Portable Mass Spectrometry

Cheung

Velásquez–García

Akinwande

2010

J. Microelectromech. Syst.

View full text Add to dashboard Cite

show abstract

“…Such an arrangement has been found to decrease fringing fields around the quadrupole entrance and exit apertures, thus helping to increase ion throughput. 29 The filters can also be used as lens elements by applying a small DC voltage that is isolated from the RF potential via high-voltage blocking resistors. The entire rod system is mounted inside a stainless steel canister that is held at ground potential.…”

Section: Methodsmentioning

confidence: 99%

“…The filters are inductively coupled to the RF from the main rod system. Such an arrangement has been found to decrease fringing fields around the quadrupole entrance and exit apertures, thus helping to increase ion throughput . The filters can also be used as lens elements by applying a small DC voltage that is isolated from the RF potential via high-voltage blocking resistors.…”

Section: Methodsmentioning

confidence: 99%

Gas-Phase Reactivity of the Ti₈C₁₂⁺Met-car with Triatomic Sulfur-Containing Molecules: CS₂, SCO, and SO₂

et al. 2006

View full text Add to dashboard Cite

Gas-phase Ti(x)C(y)+ clusters (x/y = 3/5, 4/7, 5/9, 6/9, 7/12, 8/12, 9/12) including the magic Ti8C12+ (met-car) have been produced by reactive sputtering with a magnetron cluster source. The gas-phase reactivity of the met-car with SCO, CS2, and SO2 was investigated in a hexapole collision cell by way of tandem mass spectrometry. Results indicate an increase in activity as the oxygen-to-sulfur ratio increases (SO2 > SCO > CS2) with products ranging from association to break down of the met-car cluster. Trends in the mass spectra also indicate SCO and CS2 may bond to the met-car in a unique way not observed in previous reactivity studies on Ti8C12+. To investigate this, several possible single molecule-cluster bonding configurations were calculated with density functional theory. The results indicate that bridge bonding of the intact molecules is energetically preferred. In addition, the energy barriers and transition states leading to dissociation products were calculated and the trends are found to be in qualitative agreement with experiment. The effects of the different types of bonding and number of adsorbed species on the reactivity of the met-car along with proposed reaction mechanisms for product formation are also discussed.

show abstract

“…A number of investigations [2][3][4][5][6][7][8][9] have subsequently been made into the effects of the fringe fields of quadrupole mass analysers, with special reference to prefilters. [10][11][12][13] A computer model has been written to enable the further study of quadrupole mass spectrometer behaviour, with particular reference to three-dimensional ion trajectories, both within the main filter and the entrance fields, including the effects of z-energy changes in the latter. Assessments of acceptance areas have been made from determination of successfully transmitted ion trajectories.…”

mentioning

confidence: 99%

The Effects of Entrance Fields on the Performance of Quadrupole Mass Spectrometers

Banner

2009

Eur J Mass Spectrom (Chichester)

View full text Add to dashboard Cite

The theoretical performance of quadrupole mass spectrometers has been studied by means of a new computer model, with particular reference to three-dimensional ion trajectories, both within the main filter and the entrance fields, including the effects of z-energy changes in the latter. It is shown that considerable improvements in acceptance area can be obtained by suitable modification of the entrance fields.

show abstract

Effect of a pre-filter on the sensitivity of a highresolution quadrupole mass spectrometer

Cited by 8 publications

References 6 publications

Chip-Scale Quadrupole Mass Filters for Portable Mass Spectrometry

Chip-Scale Quadrupole Mass Filters for Portable Mass Spectrometry

Gas-Phase Reactivity of the Ti₈C₁₂⁺Met-car with Triatomic Sulfur-Containing Molecules: CS₂, SCO, and SO₂

The Effects of Entrance Fields on the Performance of Quadrupole Mass Spectrometers

Contact Info

Product

Resources

About

Effect of a pre-filter on the sensitivity of a highresolution quadrupole mass spectrometer

Cited by 8 publications

References 6 publications

Chip-Scale Quadrupole Mass Filters for Portable Mass Spectrometry

Chip-Scale Quadrupole Mass Filters for Portable Mass Spectrometry

Gas-Phase Reactivity of the Ti8C12+Met-car with Triatomic Sulfur-Containing Molecules: CS2, SCO, and SO2

The Effects of Entrance Fields on the Performance of Quadrupole Mass Spectrometers

Contact Info

Product

Resources

About

Gas-Phase Reactivity of the Ti₈C₁₂⁺Met-car with Triatomic Sulfur-Containing Molecules: CS₂, SCO, and SO₂