Effect of a Nutritional Supplement Containing Vitamin E, Selenium, Vitamin C and Coenzyme Q10 on Serum PSA in Patients with Hormonally Untreated Carcinoma of the Prostate: A Randomised Placebo-Controlled Study

Hoenjet, K.M.J.L.F.; Dagnelie, Pieter C.; Delaere, K.P.J.; Wijckmans, Nicole E. G.; Zambon, J; Oosterhof, G.O.N.

doi:10.1016/j.eururo.2004.11.017

Cited by 41 publications

(32 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Wilson et al (2003) reported that although vitamin E deficiency does not alter the growth of the prostatic lobes, nor the onset and extent of lateral lobe specific prostatitis, but it may delay some differentiated functions such as secretion of specific proteins in the ventral lobe. Hoenjet et al (2005) showed that selenium may be useful in the prevention of prostate cancer. It's been reported that sesame seed has high amount calcium and phosphor (Obiajunwa et al).…”

Section: Discussionmentioning

confidence: 99%

Effect of Sesame-Supplemented Diet on Prostate and Seminal Vesicle Histology of Adult Rat

2016

View full text Add to dashboard Cite

MAHABADI, J. A.; BAFRANI, H. H. & NIKZAD, H.Effect of sesame-supplemented diet on prostate and seminal vesicle histology of adult rat. Int. J. Morphol., 34(2):604-609, 2016. SUMMARY:Infertility is a great concern among the people of reproductive age. The use of natural products obtained from traditional herbs is appealing. Studies show that antioxidants are important in improving male infertility. Thirty adult male rats were randomly divided into two regimen and control groups. The regimen group received diet containing 30 % sesame seed, while the control group received standard diet for 12 weeks. Histology of prostate and seminal vesicle were evaluated and serum levels of FSH, LH and testosterone concentrations were assessed as well. The results showed that, the diameter of peripheral epithelium and the volume density of the prostate epithelium increased but the volume density of the prostate stroma was decreased significantly in the regimen group compared to the control group. Central epithelium diameter and the volume density of the prostate lumen did not change significantly between two groups. In seminal vesicle, volume density of fibromascular and lumen decreased significantly in regimen group compared to control group. FSH and Testosterone level did not change while LH concentration increased significantly in the regimen group compared to the control group (P <0.03). This study shows that the sesame seed might improve male rat reproductive systems by histopathological changes in prostate and seminal vesicle.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of Sesame-Supplemented Diet on Prostate and Seminal Vesicle Histology of Adult Rat

2016

View full text Add to dashboard Cite

show abstract

“…The 11 randomized diet-related clinical trials conducted to date are summarized in Table 1. The trials of single dietary constituents are featured fi rst [25], followed by those that tested multiple components [26][27][28][29][30], and fi nally trials involving functional foods [31][32][33][34] and multi-behavior interventions involving diet, exercise, and stress-management therapies [35•]. These 11 trials provide examples of the most rigorous dietary intervention trials conducted to date regarding prostate cancer, but there are still signifi cant limitations.…”

Section: Introductionmentioning

confidence: 99%

Dietary interventions in prostate cancer

Demark‐Wahnefried

2008

Curr prostate rep

View full text Add to dashboard Cite

“…Vitamin E can be in the form of phenoxy or phenoxyl free radical, in unreversible intermediate reactions that presuppose the transformation of the vitamin to its final harmless products. Tocopherols and selenium act synergistically allowing the organism to have its antioxidant activity (Hoenyet et al, 2005). Selenium is required for the normal pancreatic function (Rayman, 2000), which is necessary for the proper digestion of lipids.…”

Section: Exogenous Systemsmentioning

confidence: 99%