2022
DOI: 10.3390/dj10090166
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Effect of a Novel Betel Leaf Dentifrice on Commonly Seen Oral Hygiene Parameters—A Randomized Clinical Crossover Study

Abstract: The use of herbal medicine in dentistry has grown exponentially over time. Currently, herbal medicine is considered an effective oral hygiene aid. The objective of the current study is to assess the anti-plaque efficiency and reduction of gingival bleeding of betel leaf and miswak (Salvadora persica) toothpaste. This randomized clinical cross-over pilot study enrolled 60 individuals with mild gingivitis. They were segregated into two groups by drawing lots. The study lasted 20 days and included a two-week wash… Show more

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Cited by 4 publications
(2 citation statements)
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References 28 publications
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“…Multiple physiological pathways might explain the direct effects of betel quid use and anemia suggested by our findings. Betel quid use might cause irritation or blood loss in the mouth or gastrointestinal tract, which could lead to anemia [ 47 , 48 ]. Using betel quid might also have direct physiological effects on hemoglobin production, erythropoiesis, or erythrocyte longevity, or adversely affect these via oxidative stress [ 49 ].…”
Section: Discussionmentioning
confidence: 99%
“…Multiple physiological pathways might explain the direct effects of betel quid use and anemia suggested by our findings. Betel quid use might cause irritation or blood loss in the mouth or gastrointestinal tract, which could lead to anemia [ 47 , 48 ]. Using betel quid might also have direct physiological effects on hemoglobin production, erythropoiesis, or erythrocyte longevity, or adversely affect these via oxidative stress [ 49 ].…”
Section: Discussionmentioning
confidence: 99%
“…The latter preparation of BQ without added areca nut or SLT poses negligible hazard to oral or general health and the literature provides no data on any ill effects of consuming betel leaf. On the contrary, plenty of literature is available on its medical benefits (Rai et al, 2011, Ali et al, 2022, Aara et al, 2020. On the other hand, the preparation constituting areca nut and/or SLT has been categorised as a class I carcinogen by WHO.…”
Section: Dear Editormentioning
confidence: 99%