Effect of a Home-Based Exercise Program on Indices of Physical Function and Quality of Life in Elderly Maintenance Hemodialysis Patients

Abstract

<b><i>Background:</i></b> Patients on maintenance hemodialysis (MHD) exhibit muscle wasting and impaired physical function which can be reversed with regular exercise, but accessibility to exercise programs for this unique population is lacking. We assessed the efficacy of a home-based exercise program on a broad range of indices of physical function, quality of life (QoL), and cognitive decline in patients with MHD. <b><i>Design and Methods:</i></b> Twenty-eight MHD patients, mean age 66 ± 7 years, were randomized to a 12-week home-based, case-managed aerobic and resistance exercise program or to usual care (13 exercise and 15 usual care). Comparisons were made for peak VO<sub>2</sub>, ventilatory inefficiency, 6-min walk test (6MWT), 1-min sit-to-stand (1STS), muscle strength, body composition, QoL, and cognitive measures. <b><i>Results:</i></b> Peak VO<sub>2</sub> improved significantly in the exercise group (<i>p</i> = 0.01 between groups); exercise time improved by 41 and 36% at the ventilatory threshold and peak exercise, respectively (<i>p</i> < 0.01 between groups), but there were no differences in ventilatory efficiency. Trends for improvements in 6MWT and 1STS in the exercise group were observed, but no differences were observed in strength or body composition. Among measures of QoL, general health determined by the SF-36 improved in the exercise group, but there were no differences between groups in cognitive function. <b><i>Conclusions:</i></b> MHD patients improved exercise capacity and some indices of QoL following a 12-week home-based exercise program. Home-based exercise is feasible for patients undergoing MHD and may help to obviate accessibility barriers to regular exercise.

Effect of Exercise on Health-Related Quality of Life in Patients with End-Stage Renal Disease

“…There were five studies out of the 21 included in a meta-analysis that showed an increase in the SF-36 physical component score after exercise training, with a mean increase of 10%. In spite of the fact that the overall SF-36 physical component score changed little, the exercise group's physical component score increased by 43% [74].…”

“…The SF-36 domains of physical functioning, role physical, and role emotional all increased over time as a result of exercise training, resulting in remarkable improvements in overall health. After the exercise intervention, all five dimensions of Kidney Disease Quality of Life improved [74]. The EXITE (Exercise Introduction to Enhance Dialysis Performance) experiment found that MHD patients' functional status improved after a simple, personalised six-month home-walking programme.…”

The Contribution of Exercise in Telemedicine Monitoring in Reducing the Modifiable Factors of Hypertension—A Multidisciplinary Approach

“…Reasons for their exclusion included the following: not including hypertensive participants and/or participants that were on antihypertensive medication (n = 333); not including a physical exercise intervention nor physical activity recommendation (n = 56); not including blood pressure self-management (n = 4); not including a lifestyle change intervention (n = 2); not including the delivery of health services via remote telecommunications (n = 3); not including an exercise physiologist, physical therapist, physiotherapists or a certified trainer supervision (n = 49). Finally, 19 articles were included in this systematic review [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38], as shown in Figure 1. Two of the studies were carried out by the same first author [21,22], and despite some overlapping data as a result of a common prospective randomized controlled trial, the sample and main outcomes are different.…”

“…physiotherapists or a certified trainer supervision (n = 49). Finally, 19 articles were cluded in this systematic review [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38], as shown in Figure 1. Two of the studies we carried out by the same first author [21,22], and despite some overlapping data as a res of a common prospective randomized controlled trial, the sample and main outcomes a different.…”

Anais Do I Congresso Luso-Brasileiro De Atenção Integral À Saúde (On-Line) - Resumos Expandidos

“…Estes pacientes, por vezes, têm redução da mobilidade e dificuldades de transporte. Tais situações de privação da realização de atividades físicas têm demonstrado impacto negativo em sua qualidade de vida (MYERS et al, 2021).…”