Effect of 3 years of SAFE (surgery, antibiotics, facial cleanliness, and environmental change) strategy for trachoma control in southern Sudan: a cross-sectional study

Ngondi, Jeremiah; Onsarigo, Alice; Matthews, Fiona E.; Reacher, Mark; Brayne, Carol; Baba, Samson; Solomon, Anthony W.; Zingeser, J.; Emerson, Paul M.

doi:10.1016/s0140-6736(06)69202-7

Cited by 59 publications

(49 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…118 Although the results lack the precision of a formal clinical trial, they reflect a real world situation. Similar success is reported from southern Zambia.…”

Section: Trachoma Control and The Safe Strategymentioning

confidence: 96%

“…Recent studies further confirm the additional benefit of health education programmes promoting facial cleanliness. 117,118 The E component, environmental improvement, covers a very broad category of potential activities, and in some ways is the most difficult component of the SAFE strategy to comprehend and define.…”

Section: Trachoma Control and The Safe Strategymentioning

confidence: 99%

See 1 more Smart Citation

Doyne Lecture: trachoma, is it history?

Taylor

2009

Eye

View full text Add to dashboard Cite

Trachoma has been known since pre-Pharaonic times and this infectious cause of blindness is targeted by the World Health Organization (WHO) for elimination by 2020. During the 19th century, trachoma was a major political problem in European countries as an important cause of disability in both soldiers and among the urban poor in the slums created by the Industrial Revolution. Even 100 years ago, trachoma was a major problem worldwide. Trachoma has now been eliminated from most developed regions, but the disease still affects some 150 million people in 56 developing countries. This paper reviews our current understanding of trachoma and the key strategies for the elimination of trachoma as a major blinding disease.

show abstract

“…118 Although the results lack the precision of a formal clinical trial, they reflect a real world situation. Similar success is reported from southern Zambia.…”

Section: Trachoma Control and The Safe Strategymentioning

confidence: 96%

Section: Trachoma Control and The Safe Strategymentioning

confidence: 99%

Doyne Lecture: trachoma, is it history?

Taylor

2009

Eye

View full text Add to dashboard Cite

show abstract

“…Publikovani podaci ukazuju da sprovođenje SAFE strategije, čak i u zemljama gde je na-jviše rasprostranjen trahom kao npr. Južni Sudan, smanjuje prevalenciju aktivne bolesti [37].…”

Section: Pregledni Radoviunclassified

Chlamydia trachomatis as a cause of trachoma

Maric¹,

Đukić²

2015

Praxis Med

View full text Add to dashboard Cite

Trahom (Trachoma) je specifični zarazni keratokonjunktivitis prouzrokovan serotipovima A, B, Ba i C Chlamydia trachomatis. Trahom predstavlja najčešći uzrok preventibilnog slepila u svetu pored katarakte i glaukoma. Oko 84 miliona ljudi ima aktivni trahom, 7,6 miliona ljudi sa neoperisanom i netretiranom trihijazom trpi posledice trahoma a 1,3 miliona ljudi je slepo. Danas je prihvaćena klasifikacija Svetske zdravstvene organizacije (SZO) koja koristi gradiranje na osnovu prisustva ili odsutva 5 kliničkih znakova. SZO ima program za eradikaciju slepila u svetu do 2020. godine koji se zove "Pravo na vid". U okviru tog programa nalazi se i program za eradikaciju trahoma u svetu, takozvana SAFE strategija. Ona podrazumeva hiruršku korekciju komplikacija kod trahoma (S-surgery), primenu antibiotika (A-antibiotic), higijenu lica (F-face) i rad na poboljšanju socijalno-ekonomskih i higijenskih uslova života (E-education). Lečenje trahoma sprovodi se lokalnom i sistemskom primenom odgovarajućih antibiotika. Komplikacije trahoma kao što je trihijaza rešavaju se hirurškom korekcijom i na taj način sprečavaju pojavu kornealnih zamućenja i dodatni gubitak vida. SUMMARYITrachoma is keratoconjunctivitis caused by ocular infection with Chlamydia trachomatis. Endemic trachoma is caused by serovars A, B, Ba and C. Trachoma is probably the third most common cause of blindness worldwide, after cataracta and glaucoma. Active trachoma affects an estimated 84 million people; another 7.6 million have end-stage disease, of which about 1.3 million are blind. Most trachoma programmes use the WHO simplified grading system, by presence or absence of five clinical signs. The World Health Organization is leading a global effort to eliminate blinding trachoma by the year 2020, through the implementation of the SAFE strategy. This involves surgery for trichiasis (S-surgery), antibiotics for infection (A-antibiotic), facial cleanliness (F-face) and environmental improvements to reduce transmission of the organism (Eeducation). Tratment for trachoma includes local and systemic administration of appropriate antibiotics. Surgical correction of trachomatous trichiasis reduces the risk of progressive corneal opacification and blindness.

show abstract

“…However, literature on effectiveness of the whole SAFE as an intervention package is scarce. Recent comprehensive evaluations by Ngondi et al 13 14 showed that SAFE might be effective in reducing trachoma in Southern Sudan and Northern Ethiopia. The need for huge sample sizes to determine prevalence of trichiasis has so far limited evaluation of the surgical arm of SAFE.…”

mentioning

confidence: 99%