Effect of 3-Amino-1,2,4-Triazole on the Synthesis of Riboflavin

Sund, Kenneth A.; Little, Henry N.

doi:10.1126/science.132.3427.622

Cited by 13 publications

(2 citation statements)

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“…The present investigation with E, ashbyii indicates that 3-amino-1, 2, 4-triazole can pre vent riboflavin yield without influencing the growth, which agrees with the finding with Sund and Little (24).…”

Section: Effects Of Chloramphenicol On Growth and Riboflavinogenesissupporting

confidence: 82%

Effects of 8-Azaguanine, Chloramphenicol and 3-Amino-1, 2, 4-Triazole on Riboflavin Formation by Eremothecium Ashbyii

Mitsuda

Suzuki

1970

J. Vitaminol

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Section: Effects Of Chloramphenicol On Growth and Riboflavinogenesissupporting

confidence: 82%

Effects of 8-Azaguanine, Chloramphenicol and 3-Amino-1, 2, 4-Triazole on Riboflavin Formation by Eremothecium Ashbyii

Mitsuda

Suzuki

1970

J. Vitaminol

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“…These observations may be interpreted as evidence either A, that amitrole is a general inhibitor of purine utilization or B. that amitrole inhibits the biosynthesis of purines. The first hypothesis draws support from the evidence that amitrole probably inhibits biosynthesis of histidine (13), riboflavin (21), and possibly nucleic acids (25) and from the inhibition of 4-aminoimidazole hydrolase. an enzyme involved in purine catabolism (19).…”

Section: -2 R)mentioning

confidence: 68%

Riboflavin Nullification of Inhibitory Actions of 3-Amino-1,2,4-Triazole on Seedling Growth

Hilton

1962

Plant Physiol.

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Mode of action of thiocyanates and iodides in aminotriazole formulations

Duncan

1979

Pestic. Sci.

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Ammonium thiocyanate (I) was shown to inhibit the oxidation of aminotriazole (3‐amino‐1,2,4‐triazole) in two free‐radical generating systems: (a) riboflavin photo‐sensitised oxidation; and (b) oxidation by hydroxyl radicals. Evidence from in‐vitro studies is presented to show that I could enhance aminotriazole performance by being preferentially oxidised within the leaf, thereby preventing aminotriazole free‐radical formation and subsequent conjugation with amino acids and other compounds. This opens up the possibility of a whole new range of additives which could enhance translocation by inhibiting free‐radical reactions. A comparison of possible inhibitors revealed that cyanides, iodides and perhaps bromides may be of use in this respect. In addition to inhibiting free‐radical reactions, I and potassium iodide (II) were shown to have a considerable effect on the uptake of aminotriazole by bean leaves (Phaseolus vulgaris var. Canadian Wonder). In the absence of additives, uptake of aminotriazole was negligible (1.8%); in the presence of a 1:1 molar ratio of I or II, uptake of aminotriazole was increased to 36.6% and 54.2% respectively. At a 3:1 molar ratio of additive:aminotriazole, the respective figures were 63.5% and 81.0%. II appeared to be the more efficient of the two additives at higher humidity. However, the results and observations indicated that the situation may be reversed under low‐humidity conditions.

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Effect of 3-Amino-1,2,4-Triazole on the Synthesis of Riboflavin

Cited by 13 publications

References 1 publication

Effects of 8-Azaguanine, Chloramphenicol and 3-Amino-1, 2, 4-Triazole on Riboflavin Formation by Eremothecium Ashbyii

Effects of 8-Azaguanine, Chloramphenicol and 3-Amino-1, 2, 4-Triazole on Riboflavin Formation by Eremothecium Ashbyii

Riboflavin Nullification of Inhibitory Actions of 3-Amino-1,2,4-Triazole on Seedling Growth

Mode of action of thiocyanates and iodides in aminotriazole formulations

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