Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO2 Lattice Laser in Patients with Sunken Acne Scar

Wang, Yuyan; Wang, Yu; Zhang, Jufang; Li, Jinsheng

doi:10.1155/2022/6803988

Cited by 4 publications

(5 citation statements)

References 30 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some 14 interventions were involved in the 18 included studies ( 1 , 6 , 8 , 10 , 12 , 14 , 15 , 17 , 18 , 26 , 32 , 38 , 40 , 43 , 49 , 50 , 56 , 61 ), among which 6 were combined therapies [1064Nd + 15%VC, Er + RF, 30%SC + FCL, FCL + PRP, FCL + HA, FCL + SC-CM (stem cell-conditioned medium)] and 8 were monotherapies (1064Nd, Er, FCL, MTS, ASC, RF, 1927FTL, PDL). The network demonstrated the direct or indirect relationship between the 14 interventions.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

To evaluate the efficacy and safety of laser interventions for facial acne scars: a systematic review and Bayesian network meta-analysis

Zhao¹,

Wang²,

Li³

et al. 2022

Ann Transl Med

View full text Add to dashboard Cite

Background: There are numerous laser treatments for acne scars in clinical practice. However, there are no clinical studies comparing all laser methods to provide an evidence-based bias for clinicians to choose the best strategy. Therefore, this systematic review and network meta-analysis was conducted to explore the efficacy of different types of laser treatment on acne scars. This study can provide the most effective treatment for acne scars in clinical practice. Methods:The databases of PubMed, Embase, Cochrane Library, and Web of Science were searched from their inception to July 2022. The Cochrane risk of bias assessment tool was used to assess the bias of the included original studies. Bayesian network meta-analysis was used to investigate the efficacy of laser treatment strategies in scar improvement, cure rate, and satisfaction.Results: As shown by the results, the top 3 treatment options for scar improvement were fractional carbon dioxide laser (FCL) + platelet-rich-plasma (PRP) [surface under the cumulative ranking curve (SUCRA): 0.699], 1064Nd (1,064-nm neodymium-doped yttrium aluminum garnet picosecond laser) + 15%VC (Vitamin C; SUCRA: 0.675), and 1064Nd (SUCRA: 0.627). The standard mean difference (SMD) of FCL + PRP was −1.76 (95% CI: −3.49, −0.03), compared with that of FCL. The top 3 treatment options for improving cure rate were Er (Er:YAG laser treatment) + PRP (SUCRA: 0.873), FCL (SUCRA: 0.773), and FCL + 30% salicylic acid (30%SC) (SUCRA: 0.772). The RR of Er + PRP cure rate was 13.86 (95% CI: 1.79, 107.22), compared with non-laser radiofrequency therapy. Conclusions:The findings suggested that combined therapies should be used to treat acne scars. Er + PRP showed the highest cure rate of acne scar, followed by FCL + 30%SC or FCL monotherapy. FCL combined with PRP could improve acne scarring to the greatest extent, and 1064Nd combined with 15%VC can also exert a good effect. As for satisfaction, FCL monotherapy was the most satisfactory methods for patients, followed by PRP monotherapy. Therefore, Er + PRP and FCL + PRP can be used as the first choice for clinical treatment of acne scars. Additionally, using FCL alone is also an effective and elective treatment method due to its affordable cost and comfort.

show abstract

Section: Resultsmentioning

confidence: 99%

“…A total of 13 studies ( 10 , 12 , 24 , 33 , 41 - 44 , 46 , 48 , 50 , 52 , 56 ) reported a cure rate. A total of 12 types of interventions were included, of which 7 were combined therapy (CO 2 gas + PRP, FCL + CO 2 gas, Er + FCL, FCL + 30%SC, FCL + PRP, FCL + yifu, Er + PRP) and 5 were monotherapies (FCL, RF, MTS, PRP, ER).…”

Section: Resultsmentioning

confidence: 99%

To evaluate the efficacy and safety of laser interventions for facial acne scars: a systematic review and Bayesian network meta-analysis

Zhao¹,

Wang²,

Li³

et al. 2022

Ann Transl Med

View full text Add to dashboard Cite

show abstract

“…PRP works better when combined with laser or microneedling to treat scarring. Wang et al 39 has found that PRP combined with ultra‐pulsed CO 2 laser could effectively improve acne‐depressed scars and reduce the occurrence of adverse events. Abdel‐Maguid et al 40 showed that PRP enhanced the efficacy of FCL with increased production of dermal collagen and dermal type I collagen following its injection.…”

Section: Discussion and Expectationmentioning

confidence: 99%

Study of platelet‐rich plasma application for skin and plastic surgery in recent 20 years: A bibliometric analysis

Gao

Zheng

et al. 2023

J of Cosmetic Dermatology

View full text Add to dashboard Cite

Background In recent years, platelet‐rich plasma (PRP) has been used in plastic surgery, dermatology, and other treatment procedures worldwide. Since the number of scientific writings has been significantly increasing, it is challenging to generate a manual compilation and systematic review of PRP's therapeutic applications in dermatology and plastic surgeries. This study aimed to make a bibliometric analysis of the literature in the field and evaluate research hotspots and frontiers in this field in the past 20 years. Methods Using the Academic Search Premier and ScienceDirect defined search terms, we searched the Web of Science Core Collection (WoSCC) and Scopus databases. All data were analyzed using CiteSpace 5.8.R3 and VOSviewer, including countries, institutions, authors, keywords, cited authors, cited journals, cited references, discovered research hotspots, and frontiers. Results A total of 1931 studies were retrieved. The number of publications on PRP application in dermatology and plastic surgeries showed a yearly increase. The United States was the most significant contributor to this field, while Italy's contribution was noteworthy. The journal with the highest number of relevant articles in dermatology and plastic surgery included the Journal of Cosmetic Dermatology. However, the Wound Repair and Regeneration and International Journal of Molecular Sciences were the leading journals that should be paid attention to in the future. Author Anitua E from the Tor Vergata University of Rome published the most publications in this field. In the keyword co‐occurrence analysis, all keywords were divided into six clusters, and the most common one in recent years was “PRP for facial beauty.” Facial rejuvenation, scar, and alopecia were the main hotspots and research trends in this field. Conclusions Based on the current global trends, the use of PRP in cosmetics and skin care is receiving increasing attention from researchers and clinicians. Recently, an increasing number of articles on PRP's application in skin tissue repair have been published in the United States and Italy. The number of studies on hair loss, facial rejuvenation, and scar management is increasing, suggesting that these subjects may become research hotspots for PRP in dermatology and cosmetic surgeries in recent years.

show abstract

“…Although favourable outcomes have been achieved, the treatment process is not without challenges; for example, with prolonged drug use, adverse reactions may occur and affect the therapeutic results. In recent years, better outcomes have been achieved in the treatment of depressed keloid scars by means of an ultra‐pulsed carbon dioxide fractional laser 13,14 . An ultrapulse carbon dioxide dot matrix laser can induce fractional photothermolysis in the treatment area, vaporise the scar tissue, and stimulate neogenesis and rearrangement of subcutaneous collagen fibres, thus promoting a healing response in the dermal traumatic tissue and improving local symptoms 15 .…”

Section: Introductionmentioning

confidence: 99%

“…In recent years, better outcomes have been achieved in the treatment of depressed keloid scars by means of an ultra-pulsed carbon dioxide fractional laser. 13,14 An ultrapulse carbon dioxide dot matrix laser can induce fractional photothermolysis in the treatment area, vaporise the scar tissue, and stimulate neogenesis and rearrangement of subcutaneous collagen fibres, thus promoting a healing response in the dermal traumatic tissue and improving local symptoms. 15 However, photothermolysis may also produce adverse reactions such as erythema, stinging, edema, and hyperpigmentation.…”

Section: Introductionmentioning

confidence: 99%

Ultrapulse carbon dioxide dot matrix laser for facial scar treatment: A meta‐analysis

Yan,

Sun,

et al. 2023

International Wound Journal

View full text Add to dashboard Cite

A meta‐analysis was performed to investigate the efficacy of ultrapulse carbon dioxide dot matrix laser treatment for patients with facial scars. PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure, China Biomedical Literature Database, and Wanfang Database were systematically searched for randomised controlled trials (RCTs) investigating ultrapulse carbon dioxide dot matrix laser treatment for facial scars, and the search was conducted from the time of database inception to July 2023. The retrieved literature was screened independently by two researchers, and data extraction and quality assessments were performed. The meta‐analysis was conducted using RevMan 5.4 software. Outcome metrics included overall treatment effectiveness, complication rate, and Echelle d'évaluation clinique des cicatrices d'acné (ECCA) scores. Seventeen RCTs comprising 3703 patients were included, with 1853 patients in the experimental group and 1850 in the control group. The results showed that the experimental group had significantly increased overall treatment efficacy rates (odds ratio [OR]: 3.84, 95% confidence interval [CI]: 3.02–4.90, p < 0.001), reduced complication rates (OR: 0.35, 95% CI: 0.27–0.44, p < 0.001), and improved ECCA scores (standardised mean difference: −1.79, 95% CI: −2.53 to −1.05, p < 0.001) compared with the control group. In conclusion, as the primary treatment modality for facial acne depression scars, ultrapulse carbon dioxide dot matrix laser can significantly increase the overall treatment efficacy rate and ECCA scores and reduce the incidence of complications; however, higher‐quality studies are needed for further validation.

show abstract

Effect and Safety Analysis of PRP and Yifu Combined with Ultrapulsed CO2 Lattice Laser in Patients with Sunken Acne Scar

Cited by 4 publications

References 30 publications

To evaluate the efficacy and safety of laser interventions for facial acne scars: a systematic review and Bayesian network meta-analysis

To evaluate the efficacy and safety of laser interventions for facial acne scars: a systematic review and Bayesian network meta-analysis

Study of platelet‐rich plasma application for skin and plastic surgery in recent 20 years: A bibliometric analysis

Ultrapulse carbon dioxide dot matrix laser for facial scar treatment: A meta‐analysis

Contact Info

Product

Resources

About