Effect and molecular mechanism of Sulforaphane alleviates brain damage caused by acute carbon monoxide poisoning:Network pharmacology analysis, molecular docking, and experimental evidence
Ao‐Chun Yue,
Xu‐Dong Zhou,
Hui‐Ping Song
et al.
Abstract:Sulforaphane (SFN) has attracted much attention due to its ability on antioxidant, anti‐inflammatory, and anti‐apoptotic properties, while its functional targets and underlying mechanism of action on brain injury caused by acute carbon monoxide poisoning (ACOP) have not been fully elucidated. Herein, we used a systematic network pharmacology approach to explore the mechanism of SFN in the treatment of brain damage after ACOP. In this study, the results of network pharmacology demonstrated that there were a tot… Show more
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