EFEK EKSTRAK ETANOL RIMPANG TEMUGIRING (Curcuma heyneana val) TERHADAP KADAR TRIGLISERIDA

Widyaningsih, Wahyu

doi:10.12928/pharmaciana.v1i1.516

Cited by 10 publications

(11 citation statements)

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“…The main important part of this plant which has pharmacological properties is the rhizome. C. heyneana rhizome is yellow in color (Widyaningsih, 2013). Rhizomes of C. heyneana have some pharmacological properties.…”

Section: Antioxidant Activity Of Curcuma Heyneana In Vitromentioning

confidence: 99%

“…The volatile oil has the ability to kill Fasciola hepatica worms (Woelansari et al, 2013). Widyaningsih (2013) reported that ethanolic extract of C. heyneana rhizomes could decrease triglyceride level. C. heyneana rhizomes have chemical components such as volatile oil 0.8-3%, amylum, lipids, saponin, yellow pigment, and flavonoid.…”

Section: Antioxidant Activity Of Curcuma Heyneana In Vitromentioning

confidence: 99%

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Review on in vitro antioxidant activities of Curcuma species commonly used as herbal components in Indonesia

Rohman¹,

Widodo²,

Lukitaningsih³

et al. 2019

Food Res.

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Free radicals, reactive nitrogen species (RNS) and reactive oxygen species (ROS) have been known to contribute several degenerative diseases such as cardiovascular diseases, aging, certain types of cancers, rheumatoid arthritis, neurodegenerative, and diabetes mellitus. In order to overcome the negative effects of these radicals, some scientists have explored some natural antioxidants from plants and it's by-products. The antioxidant can be defined as any substances or samples capable of inhibiting free radical reactions in the oxidation reaction. Due to curcuminoids contained, Curcuma species such as Curcuma longa, Curcuma heyneana, Curcuma mangga, and Curcuma xanthorriza were commonly used for herbal components in some traditional medicine. Several in vitro tests been introduced and used to measure antioxidant activities, namely radical scavenging assay using 2,2’-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis-(3-ethylbenzothiazoline-6 -sulfonic acid) (ABTS•+), ferric reducing antioxidant power (FRAP), ferric-thiocyanate, phosphomolybdenum method, cupric ion reducing antioxidant capacity, metal chelating power, beta-carotene bleaching linoleic-ferric-thiocyanate, and thiobarbituric acid methods. This review highlighted the antioxidant activities in vitro of C. longa, C. heyneana, C. mangga, and C. xanthorriza through several tests. To perform this review, several repute databases were analyzed and used. From this review, it can be stated that Curcuma species have powerful antioxidant activities, therefore they could be potential sources of natural antioxidants and can be used as food supplements.

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Section: Antioxidant Activity Of Curcuma Heyneana In Vitromentioning

confidence: 99%

Section: Antioxidant Activity Of Curcuma Heyneana In Vitromentioning

confidence: 99%

Review on in vitro antioxidant activities of Curcuma species commonly used as herbal components in Indonesia

Rohman¹,

Widodo²,

Lukitaningsih³

et al. 2019

Food Res.

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show abstract

“…Gaya hidup tersebut dapat menyebabkan menumpuknya lemak di dalam tubuh dan dapat menyebabkan berbagai macam penyakit seperti hipertensi, hiperkolesterolemia, serta dapat memicu terjadinya penyakit jantung koroner. 1 Aterosklerosis adalah penyakit dimana terjadi penimbunan plak di dalam arteri, sehingga pasokan oksigen berkurang, dan hiperkolesterolemia merupakan faktor risiko penting terjadinya ateroklerosis. 3 Penyakit kardiovaskuler, utamanya penyakit jantung koroner (PJK) menyebabkan banyak kematian di dunia.…”

Section: Pendahuluanunclassified

Bitter Leaves Ethanol Extract (Vernonia amygdalina) Decreases Total Cholesterol Serum Level of Hypercholesterolemic Male Wistar Rats

Hasan

Subroto²,

Puspasari³

2018

Journal of Medicine and Health

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Hypercholesterolemia is an important risk factors of atherosclerosis. Bitter leaf is believed to have potency in decreasing plasma lipid. The aim of this study is to study the effect of bitter leaf ethanol extract in decreasing total cholesterol serum levels on hypercholesterolemic male Wistar rats. This is a true experimental laboratory study with complete randomized design. Antidyslipidemia effect was tested with HFF induction and Propiltiourasil 0,01% towards 30 rats which were divided into 6 groups: groups I as normal control (standard diet), groups II, III, and IV were given bitter leaf ethanol extract of 100 mg/kgBW, 200 mg/kgBW, and 400 mg/kgBW dose, group V as positive control group with Simvastatin, and group VI as negative with aquades. HFF were given for 14 days then the study was continued for 14 days. The percentage data of the declining total cholesterol levels before and after treatments is analyzed with ANAVA, continued with LSD test. The result between group II, III, and IV with group VI shows a significant difference p<0,01. We concluded bitter leaf ethanol extract can decrease the level of total cholesterol serum of hypercholesterolmic Wistar rats.

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“…Banyak penelitian yang telah menyatakan bahwa senyawa flavonoid memiliki potensi sebagai antioksidan karena memiliki gugus hidroksil yang terikat pada karbon cincin aromatik sehingga dapat menangkap radikal bebas (Hamid et al, 2010). Menurut Widyaningsih (2011) senyawa kurkumin juga memiliki sifat antioksidan. Alrawaiq and Abdullah (2014) menyatakan bahwa kemampuan kurkumin dalam menangkal radikal bebas didukung oleh adanya gugus fenol (OH).…”

Section: Pendahuluanunclassified

Perbandingan Kadar Fenolik Total Sari Rimpang Temu Giring (Curcuma heyneana) Segar dan Terfermentasi

Murelina¹,

Wijayanti²

2018

JC-T

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Temu giring (Curcuma heyneana) telah lama digunakan oleh masyarakat Indonesia terutama untuk menjaga kesehatan kulit. Kandungan fenolik yang terdapat dalam temu giring memiliki khasiat sebagai antioksidan. Fermentasi diketahui dapat meningkatkan aktivitas antioksidan karena adanya peningkatan kadar senyawa fenolik. Tujuan penelitian ini untuk mengetahui perbandingan kadar senyawa fenolik total sari rimpang temu giring segar dan terfermentasi (Curcuma heyneana). Tahap penelitian ini meliputi penyaringan rimpang temu giring, fermentasi temu giring, identifikasi fitokimia, penetapan kadar fenolik total, analisis data dan membuat kesimpulan. Pembuatan sari temu giring dilakukan dengan menyari temu giring dengan air sampai didapatkan sari. Dilanjutkan dengan fermentasi menggunakan bakteri Lactobacillus bulgaricus selama 24 jam dengan suhu 37°C. Pengujian organoleptis meliputi warna, bau, rasa dan pH. Hasil pH sari segar dan terfermentasi mengalami penurunan. Pengujian identifikasi fitokimia temu giring segar dan terfermentasi positif mengandung fenolik dan flavonoid. Tahap penetapan kadar total fenolik total dengan metode Folin-Ciocalteu didapatkan sari temu giring segar sebesar 9.476± 2.04 mgGAE/gram dan sari temu giring terfermentasi sebesar 61.333±1.643 mgGAE/gram. Kesimpulan dari penelitian ini adalah terdapat perbedaan kadar fenolik total sari temu giring segar dan terfermentasi yang mengalami peningkatan setelah difermentasi. Kata-kata kunci: fenolik, fermentasi, temu giring

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EFEK EKSTRAK ETANOL RIMPANG TEMUGIRING (Curcuma heyneana val) TERHADAP KADAR TRIGLISERIDA

Cited by 10 publications

References 0 publications

Review on in vitro antioxidant activities of Curcuma species commonly used as herbal components in Indonesia

Review on in vitro antioxidant activities of Curcuma species commonly used as herbal components in Indonesia

Bitter Leaves Ethanol Extract (Vernonia amygdalina) Decreases Total Cholesterol Serum Level of Hypercholesterolemic Male Wistar Rats

Perbandingan Kadar Fenolik Total Sari Rimpang Temu Giring (Curcuma heyneana) Segar dan Terfermentasi

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