Efeitos do etil‐2‐cianoacrilato e do butil‐2‐cianoacrilato no processo de consolidação óssea em ratos. Estudo experimental controlado

Palácio, Evandro Pereira; Pereira, Gilberto José Cação; Silvares, Paulo Roberto de Almeida; Stasi, G; Staut, Caio de Andrade; Sardenberg, Trajano

doi:10.1016/j.rbo.2016.12.007

Cited by 4 publications

(1 citation statement)

References 11 publications

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“…We bonded a 500-μm dentin disk to the bottom of the quartz chamber using cyanoacrylate adhesive and seeded hPDCs onto the surface of the dentin disk, mimicking the interrelationship between the remaining dentin and hDCPs in deep caries. Cyanoacrylate adhesive was chosen as the adhesive material between the dentin disk and the quartz chamber due to its several advantages, including rapid curing, excellent biocompatibility, and hydrophobicity [26,27].…”

Section: Discussionmentioning

confidence: 99%

In vitro effect of Er: YAG laser irradiation in caries cavity preparation on biobehaviors of adjacent human dental pulp cells in the pulp chamber

Wang,

Li,

Wang

et al. 2024

Journal of Biophotonics

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The erbium‐doped yttrium aluminum garnet (Er: YAG) laser has been successfully applied in caries removal; however, little is known about proper parameters of Er: YAG laser on different conditions of caries removal, especially the influence of Er: YAG irradiation on human dental pulp cells (hDPCs). Here, we tested the effects of Er: YAG laser at different output energy levels (100, 200, 300, 400, and 500 mJ) on biobehaviors of hDPCs. To simulate clinical deep caries conditions, hDPCs were cultured on the pulpal side of 500‐μm‐thick dentin disks in an in vitro pulp chamber model. Temperature change, structural change, and ablation depth of dentin disk were also recorded. The findings suggested that the biological behaviors of hDPCs are strongly correlated with the energy output of the Er: YAG laser. Er: YAG laser irradiation at 100 mJ may be proper and safe for deep caries removal since it would not cause any adverse effect on hDPCs biobehaviors.

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Section: Discussionmentioning

confidence: 99%

In vitro effect of Er: YAG laser irradiation in caries cavity preparation on biobehaviors of adjacent human dental pulp cells in the pulp chamber

Wang,

Li,

Wang

et al. 2024

Journal of Biophotonics

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Flexible Osteogenic Glue as an All‐In‐One Solution to Assist Fracture Fixation and Healing

Tang

Chen

et al. 2021

Adv Funct Materials

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Osteogenic glue that reproduces the natural bone composition represents the final frontier of orthopedic adhesives with the potential to revolutionize surgical strategies against comminuted fractures. However, it is difficult to achieve an all-in-one formula, which could provide flexible and reliable adhesiveness while avoiding interfering with or even promoting the healing of glued fractures. Herein, an osteogenic glue characterized by inorganic-in-organic integration between amine-modified mesoporous bioactive glass nanoparticles (AMBGN) and bioadhesive gelatin-dextran network (GelDex) is introduced as an all-in-one tool to flexibly adhere and splice bone fragments and subsequently guide fracture healing during degradation. Relying on such integration, a 4-fold improvement in cohesiveness is presented, followed by a nearly 5-fold enhancement in adhesive strength in ex vivo porcine bone samples. The reversible and re-adjustable adhesiveness also enables glue to effectively splice intricate fragments from highly comminuted fractures in the rabbit radius in an in vivo environment. Moreover, well-preserved organic-inorganic integrity during degradation of the glue guides sustained interfacial osteogenesis and achieve satisfying healing outcomes in glued fractures, as observed by the 2-fold improvement in biomechanical and radiological performance compared with commercially available cyanoacrylate adhesives. The current findings propose an all-in-one solution for the fixation of bone fragments during surgery.

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Bioactive Pore‐Forming Bone Adhesives Facilitating Cell Ingrowth for Fracture Healing

Gao

Zhou

et al. 2020

Advanced Materials

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The effectiveness of commercial bone adhesives is known to be hampered by the weak efficacy of cell ingrowth. The strategy of macropore‐forming, especially bioactive macropores, holds considerable promise to circumvent this problem, thereby promoting fracture healing. Herein, a class of bioactive glass‐involved macropore‐embedded bone adhesives is developed, which is capable of facilitating the migration of bone‐derived mesenchymal stromal cells into the adhesive layer and differentiation into osteocytes. The integration of bioactive glass‐particle‐encapsulated porogens in the bone adhesives is key to this approach. A robust instant bonding on the bone adhesive and a high efficiency of bone regeneration on a mouse skull are observed, both of which are vital for clinical applications and personalized surgical procedures. This work represents a general strategy to design biomaterials with high cell‐ingrowth efficacy.

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Efeitos do etil‐2‐cianoacrilato e do butil‐2‐cianoacrilato no processo de consolidação óssea em ratos. Estudo experimental controlado

Cited by 4 publications

References 11 publications

In vitro effect of Er: YAG laser irradiation in caries cavity preparation on biobehaviors of adjacent human dental pulp cells in the pulp chamber

In vitro effect of Er: YAG laser irradiation in caries cavity preparation on biobehaviors of adjacent human dental pulp cells in the pulp chamber

Flexible Osteogenic Glue as an All‐In‐One Solution to Assist Fracture Fixation and Healing

Bioactive Pore‐Forming Bone Adhesives Facilitating Cell Ingrowth for Fracture Healing

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