Efeito do uso profilático do anti-inflamatório não-esteroide ibuprofeno sobre o desempenho em uma sessão de treino de força

Corrêa, Cleiton Silva; Cadore, Eduardo Lusa; Baroni, Bruno Manfredini; Silva, Eduardo Ramos da; Bijoldo, Jocelito Martins; Pinto, Ronei Silveira; Kruel, Luiz Fernando Martins

doi:10.1590/s1517-86922013000200009

Cited by 7 publications

(4 citation statements)

References 28 publications

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“…Em um ensaio clínico acerca do efeito do uso profilático do ibuprofeno no desempenho do treino de força, esse medicamento não atuou na promoção de qualquer efeito benéfico nesse viés, evidenciando ainda riscos do seu uso indiscriminado como distúrbios hidroeletrolíticos, nefrotoxicidade e fadiga muscular (CORREA, et al 2013).…”

Section: Resultsunclassified

A Importância Da Orientação Farmacêutica No Uso Racional Do Ibuprofeno: Revisão Sistemática

Gomes,

Costa,

Souza

et al. 2023

Rev. Foco

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Introdução: O ibuprofeno pertence a classe dos anti-inflamatórios não esteroidais, pode provocar efeitos adversos e seu uso deve ser feito sob orientação de um profissional de saúde. Objetivo geral: realizar uma revisão sistemática sobre a importância da orientação farmacêutica relacionada ao uso do ibuprofeno. Metodologia: Trata-se de um estudo de revisão sistemática elaborada segundo o modelo PRISMA, onde foram analisados estudos publicados entre 2013 e 2022, nas bases de dados BVS e MedLine. Resultados e discussão: Por meio das buscas nas bases de dados foram selecionados 15 estudos, dos quais buscaram reunir informações acerca dos riscos associados ao uso crônico do ibuprofeno, os fatores que levam ao seu uso inadequado e as principais ações farmacêuticas frente a essa situação. Considerações finais: Através do desenvolvimento desse estudo foi possível compreender a importância da orientação farmacêutica quando relacionado ao uso irracional do ibuprofeno, sendo evidenciado que este profissional executa ações de orientação, aconselhamento, ações educacionais, farmacovigilância e ainda através de programas de conscientização que se relacionem ao uso indiscriminado do ibuprofeno.

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Section: Resultsunclassified

A Importância Da Orientação Farmacêutica No Uso Racional Do Ibuprofeno: Revisão Sistemática

Gomes,

Costa,

Souza

et al. 2023

Rev. Foco

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“…According to Grgic et al, higher loads cause greater wear and micro injury and thus necessitate greater recovery (19). A recent double-blind, placebo-controlled study that provided 1.2 g of ibuprofen showed no statistical benefit of NSAID consumption in the number of repetitions between sets and in total training volume in the bench press and squat exercises at a load of 65% of 1 RM in young men (11). The load used in that study was low; in contrast, the load in our study was high, with potential to provoke a greater inflammatory process and neural fatigue.…”

Section: Discussionmentioning

confidence: 99%

“…Exercise intensity and time were adapted from Correa et al (11). After a 30-second warm-up at 30% of 1 RM in the horizontal bench press exercise, participants from both groups began the test session at 6:00 P.M. Each participant performed three sets of the horizontal bench press exercise at 90% of 1 RM until concentric failure, with a 1-minute inter-set rest interval.…”

Section: Strength-training Sessionmentioning

confidence: 99%

“…However, whether consumption of these drugs confers a performanceenhancing benefit remains unclear. One study showed that ibuprofen did not alter the number of repetitions performed in upper or lower limbs, indicating that its use did not alter exercise tolerance during a strength-training session (11). Another study found that ibuprofen had no effect on the histologic appearance of leukocytes in an acute resistance-training (RT) bout (10); furthermore, no effect was found on blood markers of muscle injury or subjective muscle pain.…”

Section: Introductionmentioning

confidence: 99%

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Naproxen’s Effect on Performance Within Neuromuscular Parameters

et al. 2019

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This study investigated whether naproxen has an ergogenic effect on neuromuscular performance. A randomized, double-blind, placebo-controlled, crossover trial was conducted on 11 resistance-trained men who performed one strength-training session after taking 500 mg of naproxen and another session after taking a placebo. Participants performed three sets of the horizontal bench press with a load of 90% of repetition maximum (RM) to concentric failure. Outcome variables included number of repetitions, workload, fatigue index (FI), and delayed onset muscle soreness (DOMS). Results showed a statistically insignificant reduction in the number of repetitions for placebo when compared to naproxen, amounting to a relative difference of 44.89%. DOMS was lower in the naproxen group, but differences between conditions were not statistically significant. A statistically significant treatment effect was found for workload, favoring naproxen treatment. A statistically significant difference was found for FI between the second and third sets compared to the first set, with results favoring naproxen. We concluded that naproxen helps enhance neuromuscular outcomes in an acute high-intensity strength training bout.

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Analgesics and Sport Performance: Beyond the Pain‐Modulating Effects

Holgado

Hopker

Sanabria

et al. 2017

PM&R

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1Analgesics are widely used in sport to treat pain and inflammation associated with injury. However, there 2 is growing evidence that some athletes might be taking these substances in an attempt to enhance Introduction 18There is little doubt that when exercise is performed above certain intensities, or over a prolonged period 19 of time, it causes feeling of pain and discomfort. Sayings such as 'no pain, no gain' are often heard in 20 relation to both training and competition settings across a variety of different sports. Indeed, these 21 feelings of exercise-induced pain have been shown to have a negative effect on training and performance 22 [1]. As a consequence, there has been a trend for athletes from all levels and ages to use pharmacological 23 analgesics substances prior to training and competition up to 4-fold more than their age-matched general 24 population [2]. The general term analgesic covers a variety of different pharmacological substances, 25 including non-steroidal anti-inflammatory drugs (NSAIDs), non-opioid analgesic (such as paracetamol 26 2 and others), weak opioids (for example tramadol, codeine or morphine [3]) and orally administered or 27 injected glucorticosteroids [4,5]. Indeed, paracetamol and NSAIDs are one of the most recurrent groups 28 of pharmacological substances used by athletes ranging from 11 up to 92% [6,7]. For instance, it is 29 common for athletes with minor injuries to continue training and even competing, by treating their minor 30 health issues with analgesic [8]. 31The aforementioned negative association between pain and exercise capacity increases the likelihood of 32 analgesic use as a method to increase the level of performance during competition [5,9]. Furthermore, the 33 trends for more frequent use of analgesics in-competition vs. out-competition, use of more than one drug 34 at the same time, and administration of these medications at supratherapeutic dosages, all suggest athletes 35 may be using these analgesics as ergogenic aids [4,5]. Therefore, in contrast to the post-exercise use of 36 analgesics to accelerate recovery, there is potential for their prophylactic use as a potential performance 37 enhancing intervention. In comparison to what is known about the use of analgesics for treating sporting 38 injury [10,11], much less is known about their effects on exercise related physiology and performance 39 [12][13][14]. However, as analgesics exert a pharmacological action on key physiological systems related to 40 exercise performance, a theoretical rationale exists whereby these drugs could provide a significant 41 ergogenic effect. 42 Material and methods 43The aim of this manuscript was to review the literature and evaluate the evidence for the ergogenic effect 44 of analgesics, expected dosages, and potential side effects. A computer search of scientific databases 45 (PubMed, Web of Science, ScienceDirect and Scopus) was made for English language articles 46 investigating the use of analgesics in sport for all period of time up to September 2...

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Efeito do uso profilático do anti-inflamatório não-esteroide ibuprofeno sobre o desempenho em uma sessão de treino de força

Cited by 7 publications

References 28 publications

A Importância Da Orientação Farmacêutica No Uso Racional Do Ibuprofeno: Revisão Sistemática

A Importância Da Orientação Farmacêutica No Uso Racional Do Ibuprofeno: Revisão Sistemática

Naproxen’s Effect on Performance Within Neuromuscular Parameters

Analgesics and Sport Performance: Beyond the Pain‐Modulating Effects

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