DOI: 10.26512/2014.12.t.18254
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Efeito do agonista seletivo do receptor β tireoidiano (GC-1) na tolerância ao esforço de ratos wistar submetidos ao hipotireoidismo experimental

Abstract: INTRODUCTION: Thyroid hormone (TH) has a central role in metabolic homeostasis acting on lipolysis and cholesterol control. However, HT has profound effects on the heart by its receptor α1. Thus , selective β thyroid agonists such as GC-1 , that has proven action on the metabolic rate , serum cholesterol levels and lipolysis without affecting heart rate, presented with great therapeutic value to fight diseases such as obesity and dyslipidemia. However, no study to date sought to test the action of this substan… Show more

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