Efeito alcalinizante da solução de Ringer com lactato em ovelhas sadias e acidóticas

Abstract

Efeito alcalinizante da solução de Ringer com lactato em ovelhas sadias e acidóticas [

Intravenous administration of a polyionic solution containing 84 mEq/l of lactate resolves experimentally induced hyperchloraemic acidosis in horses

“…Lactated Ringer's solution is a balanced, polyionic, crystalloid solution indicated for the simultaneous correction of dehydration and metabolic acidosis . Due to a relatively low concentration of lactate, the alkalising effect of lactated Ringer's solution has been shown to be reduced or absent in calves, sheep and healthy horses , and the inability of lactated Ringer's solution to correct experimentally induced metabolic acidosis was demonstrated in steers , ewes and calves .…”

Iatrogenic alkalosis in goats with the use of intravenous electrolyte solution containing 84 mEq/L of lactate

“…These results contradicted the concept that LRS has an alkalizing capacity (CONSTABLE, 2003;JONES & NAVARRE, 2014) and that it could be used in the treatment of metabolic acidosis in calves (SMITH & BERCHTOLD, 2014). LRS was not able to correct the metabolic acidosis of calves with diarrhea (NAKAGAWA et al, 2009) and sheep with ALRA (COSENZA et al, 2015). As LRS has a plasma-like electrolyte composition, it is expected that it will not cause electrolyte and iatrogenic acid-base changes (COSENZA et al, 2013;JUNQUEIRA et al, 2015), which was also observed in this study.…”

“…In Brazil, only lactate is reported in commercial electrolytic solutions such as lactated Ringer´s solution (LRS). Due to a low lactate concentration (28 mEq/L), the LRS alkalizing potential is reduced or absent in healthy animals (COSENZA et al, 2013;JUNQUEIRA et al, 2015), and this solution is not effective in correcting metabolic acidosis in diarrheic calves (NAKAGAWA et al, 2009) and sheep with ARLA (COSENZA et al, 2015).…”

Intoxicação por metaldeído em cão: Relato de caso

“…A fluidoterapia de escolha foi o Ringer com Lactato, já que pacientes envenenados por metaldeído apresentam acidose metabólica e este fluido proporciona uma elevação do pH em líquidos extracelulares, agindo nos casos em que há um desvio do equilíbrio ácido-básico no sentido da acidose (Cosenza et al, 2015). Como antioxidante foi utilizado a n-acetilcisteína (dose inicial 140 mg/kg e posteriormente 70 mg/kg QID), combatendo diretamente os radicais livres e aumentando as concentrações de glutationa (Ondani et al, 2011).…”