Efectividad del plasma rico en fibrina y membrana de colágeno en la regeneración ósea guiada.

Príncipe-Delgado, Yuliana; Mallma-Medina, Adrián; Castro-Rodríguez, Yuri

doi:10.4067/s0719-01072019000200063

Cited by 5 publications

(9 citation statements)

References 10 publications

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“…Randomized clinical trials have shown that the use of PRF leads to periodontal repair, with statistically conrmed superior results for intrabony defects than when PRF is not used. When using PRF, repotentiation and increased effective performance of biomaterials such as bone gras or collagen barrier membranes are shown, in addition to periodontal regeneration of intrabony defects (53,61). A case described by Miron, et al (53) showed results of the potential for tissue repair using PRF in furcation defects.…”

Section: Prf In Intrabony Defect Regenerationmentioning

confidence: 99%

From Hematology to Tissue Engineering: Current Status and Projection of Platelet Concentrates and their Derivatives

Velásquez¹,

Gamboa

2022

Univ Odontol

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Background: In the last decade, tissue engineering, cell therapy, and research advances in hematological sciences have become tools for regenerative dentistry, using platelet concentrates as the cornerstone. The results are promising, but it is necessary to consolidate the existing evidence on their real relevance and clinical impact. Purpose: To conduct an integrative review of literature to present scientific evidence on platelet concentrates, their use, characteristics, benefits, and usefulness for tissue engineering. Methods: The search for information was performed in the integrated search engine EBSCOhost, including studies published from 2010 to early 2020. Results: Most of the publications present the evolution of platelet concentrates with evaluations of their in vitro and in vivo use, clinically proving their regenerative potential in soft tissue and bone repair. Marked differences exist between platelet-rich plasma and platelet-rich fibrin. Conclusion: There is controversy and indiscriminate use of the terminology referring to platelet concentrates; however, they are not only a source of growth factors, but also a living biomaterial, based on fibrin, and its positioning as a surgical material is increasingly evident to become a tissue-oriented solution, by optimizing regeneration and healing, and an important tool of low economic profile in tissue engineering.

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Section: Prf In Intrabony Defect Regenerationmentioning

confidence: 99%

From Hematology to Tissue Engineering: Current Status and Projection of Platelet Concentrates and their Derivatives

Velásquez¹,

Gamboa

2022

Univ Odontol

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“…La función principal de la membrana oclusiva es mantener el defecto aislado de células y tejido no osteogénico, además de estimular o permitir la llegada y alojamiento de osteoblastos y otros factores estimulantes de la regeneración en la zona del defecto. En comparación a la membranas no reabsorbibles, las membranas de colágeno cumplen con criterios que aseguran 51 una adecuada regeneración ósea al permitir un mejor sellado del defecto, tener una fácil manipulación y poseer una estructura que en su parte exterior impide el alojamiento de células y tejido no osteogénico y estimula la llegada de células osteogénicas [7][8][9][10] .…”

Section: Introductionunclassified

Regeneración ósea con xenoinjerto porcino en defectos en calvaria de guinea pigs. Estudio histológico e histométrico

Real López,

Tupiza Vasconez

et al. 2023

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Entre los sustitutitos óseos, el xenoinjerto es el biomaterial más utilizado en Regeneración Ósea Guiada, su función es dar soporte a la membrana. Objetivo: evaluar in vivo la formación ósea en defectos de calvaria de cobayos, cuando se utiliza solo membrana de colágeno o membrana de colágeno más xenoinjerto mediante procedimientos de regeneración ósea guiada. Material y Métodos: En 24 cobayos fueron creados defectos de 5 mm en cada parietal (n=48), se realizó Regeneración Ósea Guiada (ROG) conformando dos grupos de estudio: xenoinjerto más membrana colágena y únicamente membrana colágena; se valoró la formación ósea a 15, 30 y 60 días más la estabilidad de la membrana. Al finalizar cada tiempo de estudio, las muestras fueron descalcificadas y preparadas para tinción con hematoxilina-eosina y tricrómico de Maisson. De un microscopio óptico con aumentos a 2X y 4X fueron obtenidas imágenes para análisis histológico e histométrico; mediante el programa ImageJ se determinó los porcentajes de neoformación ósea. En el análisis estadístico el Test de Mann Whitney fue aplicado para comparación entre grupos considerando una significancia < 0.05. Resultados: los grupos tratados solo con membrana colágena presentaron estadísticamente una mayor formación ósea en todos los tiempos de estudio (p= < 0.005), sin embargo, hacia el centro del defecto se observó colapsos de la membrana que no fueron observados en el grupo tratado con xenoinjerto donde se conservó el volumen del defecto. Conclusión: El xenoinjerto formó menor porcentaje de hueso nuevo que cuando se usó membrana de colágeno sola, sin embargo, fue más eficiente para dar soporte a la membrana que los defectos vacíos.

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“…The human body has a limited capacity to regenerate bone tissue, which is why regenerative techniques involving different biomaterials are constantly being tested to develop a tissue that is the closest in its anatomical structure and functionality to the previous one. 1 One of the most prevalent oral diseases is periodontal disease. Due to the its high prevalence, there is consensus that the approach to treat periodontal conditions must be accompanied by a focus on public health.…”

Section: Introductionmentioning

confidence: 99%

Regenerating effect of hyaluronic acid on circumferential bone defects in Wistar albino rats.

Bueno-Beltrán¹,

Budiel-Salguero²,

Palacios-Bustamante³

et al. 2021

J Oral Res

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Objective: To determine the regenerating effect of hyaluronic acid on circumferential bone defects in albino Wistar rats. Material and Methods: An experimental type study was designed and carried out with 15 albino male Wistar rats, 4 months old and weighing between 250 and 350 grams. Two circumferential bone defects 3mm in diameter and 0.8mm deep were created in the calvaria of the parietal bone (on both sides of the midline). One defect was filled with a demineralized bone matrix (control group); while the other defect was filled with the combination of a demineralized bone matrix plus hyaluronic acid (experimental group). Five experimental rats were euthanized at 30, 60 and 90 days after surgery and they were histologically evaluated following the parameters proposed by Heiple. Results: The experimental group presented a better degree of bone regeneration at 30 and 60 postoperative days. Conclusion: Hyaluronic acid is effective in bone regeneration of circumferential bone defects.

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Efectividad del plasma rico en fibrina y membrana de colágeno en la regeneración ósea guiada.

Cited by 5 publications

References 10 publications

From Hematology to Tissue Engineering: Current Status and Projection of Platelet Concentrates and their Derivatives

From Hematology to Tissue Engineering: Current Status and Projection of Platelet Concentrates and their Derivatives

Regeneración ósea con xenoinjerto porcino en defectos en calvaria de guinea pigs. Estudio histológico e histométrico

Regenerating effect of hyaluronic acid on circumferential bone defects in Wistar albino rats.

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