“…To the Editor, We appreciate Dr. Rujittika Mungmunpuntipantip and Dr. Viroj Wiwanitkit for their valuable comment about our article. 1 We found that chronic exposure to efavirenz (EFV) may be associated with increased premature ventricular contraction (PVC), premature atrial contraction (PAC) as well as decreased heart rate variability (HRV) in young human immunodeficiency virus (HIV) patients. 2 The impact of underlying genetic risk factors on the development of dysrhythmias has been partially understood.…”